Targeting CD19-Negative Relapsed B-Acute Lymphoblastic Leukemia Using Trivalent CAR T Cells

被引：0
|
作者：
Fousek, Kristen [1 ]
Watanabe, Junji [2 ]
George, Ann [2 ]
Byrd, Tiara [1 ]
An, Xingyue [3 ]
Samaha, Hebatalla [1 ]
Salsman, Vita [1 ]
Navai, Shoba [1 ]
Jang, Albert [1 ]
Kim, Hye Na [2 ]
Joseph, Sujith [1 ]
Baker, Matthew [1 ]
Varadarajan, Navin [3 ]
Hegde, Meenakshi [1 ]
Kim, Yong-Mi [2 ]
Heisterkamp, Nora [2 ]
Abdel-Azim, Hisham [2 ]
Ahmed, Nabil [1 ]
机构：
[1] Baylor Coll Med, Houston, TX 77030 USA
[2] Childrens Hosp Los Angeles, Los Angeles, CA 90027 USA
[3] Univ Houston, Houston, TX USA
来源：
MOLECULAR THERAPY | 2018年 / 26卷 / 05期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
647
引用
收藏
页码：298 / 298
页数：1
相关论文
共 50 条
  • [41] Humanized CD19-targeted chimeric antigen receptor T (CAR-T) cells for relapsed/refractory pediatric acute lymphoblastic leukemia
    Wang, Shiyuan
    Wang, Xue
    Ye, Chunying
    Cheng, Hai
    Shi, Ming
    Chen, Wei
    Qi, Kunming
    Wang, Gang
    Wu, Qingyun
    Zeng, Lingyu
    Li, Zhenyu
    Jing, Guangjun
    Zheng, Junnian
    Xu, Kailin
    Cao, Jiang
    AMERICAN JOURNAL OF HEMATOLOGY, 2021, 96 (05) : E162 - E165
  • [42] CD19 CAR T-cells for pediatric relapsed acute lymphoblastic leukemia with active CNS involvement: a retrospective international study
    Elad Jacoby
    Sara Ghorashian
    Britta Vormoor
    Barbara De Moerloose
    Nicole Bodmer
    Olga Molostova
    Asaf D Yanir
    Jochen Buechner
    Ronit Elhasid
    Bella Bielorai
    Srdan Rogosic
    Marie-Emilie Dourthe
    Michael Maschan
    Claudia Rossig
    Amos Toren
    Arend von Stackelberg
    Franco Locatelli
    Peter Bader
    Martin Zimmermann
    Jean Pierre Bourquin
    Andre Baruchel
    Leukemia, 2022, 36 : 1525 - 1532
  • [43] ACUTE LYMPHOBLASTIC LEUKEMIA: CD19-CAR-T CELLS ARE AN EFFECTIVE THERAPY FOR POSTTRANSPLANT RELAPSE
    Bader, Peter
    Rossig, Claudia
    Hutter, Martin
    Ayuk, Francis Ayuketang
    Baldus, Claudia D.
    Bueklein, Veit L.
    Bonig, Halvard
    Cario, Gunnar
    Einsel, Hermann
    Holtik, Udo
    Koenecke, Christian
    Shahrzad, Bakhtiar
    Kuenckele, Anette
    Meisel, Roland
    Mueller, Fabian
    Mueller, Ingo
    Pennack, Olaf
    Rettinger, Eva
    Sauer, Martin G.
    Schlegel, Paul-Gerhardt
    Soerensen, Jan
    von Stackelberg, Arend
    Strahm, Brigitte
    Hauer, Julia
    Freuchtinger, Tobias
    Jarisch, Andrea
    BONE MARROW TRANSPLANTATION, 2023, 58 (SUPP1) : 43 - 44
  • [44] The effect of pembrolizumab in combination with CD19-targeted chimeric antigen receptor (CAR) T cells in relapsed acute lymphoblastic leukemia (ALL)
    Maude, Shannon L.
    Hucks, George E.
    Self, Alix Eden
    Talekar, Mala Kiran
    Teachey, David T.
    Baniewicz, Diane
    Callahan, Colleen
    Gonzalez, Vanessa
    Nazimuddin, Farzana
    Gupta, Minna
    Frey, Noelle V.
    Porter, David L.
    Levine, Bruce L.
    Melenhorst, Jan J.
    Lacey, Simon F.
    June, Carl H.
    Grupp, Stephan A.
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35
  • [45] Anti-CD19/CD22 Dual CAR-T Therapy for Refractory and Relapsed B-Cell Acute Lymphoblastic Leukemia
    Yang, Junfang
    Jiang, Pengfei
    Zhang, Xian
    Zhu, Xiaobin
    Dong, Qi
    He, Jiaping
    Lin, Nanjing
    Wang, Zhenguang
    Cai, Songbai
    Ye, Xun
    Su, Yunchao
    Li, Wenqian
    Li, Jingjing
    Yu, Ziyao
    He, Jiujiang
    Xu, Li
    Song, Dan
    Cao, Wei
    Lu, Peihua
    BLOOD, 2019, 134
  • [46] CD19 CAR T-cells for pediatric relapsed acute lymphoblastic leukemia with active CNS involvement: a retrospective international study
    Jacoby, Elad
    Ghorashian, Sara
    Vormoor, Britta
    De Moerloose, Barbara
    Bodmer, Nicole
    Molostova, Olga
    Yanir, Asaf D.
    Buechner, Jochen
    Elhasid, Ronit
    Bielorai, Bella
    Rogosic, Srdan
    Dourthe, Marie-Emilie
    Maschan, Michael
    Rossig, Claudia
    Toren, Amos
    von Stackelberg, Arend
    Locatelli, Franco
    Bader, Peter
    Zimmermann, Martin
    Bourquin, Jean Pierre
    Baruchel, Andre
    LEUKEMIA, 2022, 36 (06) : 1525 - 1532
  • [47] One CAR can hide another: anti-CD22 CAR-T cells in relapsed or refractory acute b-lymphoblastic leukemia
    Cailly, Laura
    Leleu, Xavier
    Moya, Niels
    HEMATOLOGIE, 2020, 26 (01): : 9 - 10
  • [48] Potent anti-leukemia activities of humanized CD19-targeted CAR-T cells in patients with relapsed/refractory acute lymphoblastic leukemia
    Cao, J.
    Wang, G.
    Zheng, J.
    Xu, K.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 1719 - 1720
  • [49] Factors Influencing Efficacy of CD19-CAR-T Cells in Children and Adults with Relapsed/Refractory B-Cell Lymphoblastic Leukemia
    Zhai, Zhimin
    BLOOD, 2018, 132
  • [50] CD19-negative B-lymphoblastic leukemia associated with hypercalcemia, lytic bone lesions and aleukemic presentation
    Hussein, Shafinaz
    Pinkney, Kerice
    Jobanputra, Vaidehi
    Bhagat, Govind
    Alobeid, Bachir
    LEUKEMIA & LYMPHOMA, 2015, 56 (05) : 1533 - 1537
12345