Ynol Ethers: Synthesis and Reactivity

被引：4

作者：

Verrier, Charlie ^{[1
]}

Carret, Sebastien ^{[1
]}

Poisson, Jean-Francois ^{[1
]}

机构：

[1] Univ Grenoble Alpes, Dept Chim Mol SERCO, UMR 5250, CNRS,IMCG FR 2607, F-38041 Grenoble, France

来源：

CHIMIA | 2016年 / 70卷 / 1-2期

关键词：

Alkynes; Enol ethers; Ketenes; Synthesis; Ynol ethers; ACETYLENIC ETHERS; ALKYNYL ETHERS; INTRAMOLECULAR CARBOLITHIATION; ASYMMETRIC-SYNTHESIS; EFFICIENT SYNTHESIS; 2+2 CYCLOADDITION; CHEMISTRY; CARBANIONS; REAGENTS; STRATEGY;

D O I：

10.2533/chimia.2016.93

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ynol ethers are highly valuable substrates offering a wide range of reactivity. These highly electron rich heterosubstitued alkynes can be of great synthetic potential. In this mini-review, the different methods for the synthesis of ynol ethers are first presented, divided in three main approaches involving a beta-elimination, a carbene rearrangement and a direct oxidation of an alkyne. Their reactivity is then summarized underlying their synthetic utility. This non-exhaustive review aims at presenting the intrinsic reactivity of these compounds, still underexploited in synthesis.

引用

页码：93 / 96

页数：4

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