The Effect of Bevacizumab-Related Hypertension on the Prognosis of Patients with Colorectal Cancer and Non-Small Cell Lung Cancer

被引:0
|
作者
Pan, Juhua [1 ]
Zheng, Liangda [2 ]
Liu, Binghui [1 ]
You, Shuqing [1 ]
Zheng, Weizhi [1 ]
机构
[1] Taizhou First Peoples Hosp, Dept Pathol, Taizhou 318020, Zhejiang, Peoples R China
[2] Taizhou First Peoples Hosp, Dept Hematol, Taizhou 318020, Zhejiang, Peoples R China
关键词
Bevacizumab; hypertension; colorectal cancer; non-small cell lung cancer; prognosis;
D O I
10.36468/pharmaceutical-sciences.spl.448
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
To study and analyze the effect of bevacizumab-related hypertension on the prognosis of patients with colorectal cancer and non-small cell lung cancer. The study randomly selected 100 colorectal cancer patients and 100 non-small cell lung cancer patients who received therapy in our hospital from October 2019 to October 2021. Among them, adopted intervention for 100 colorectal cancer patients with bevacizumab combined with cytotoxic drug chemotherapy and adopted intervention for 100 non-small cell lung cancer patients with bevacizumab combined with standard chemotherapy. Bevacizumab treatment has better therapeutic effect of hypertension on colorectal cancer patients than non-small cell lung cancer patients. Compared with colorectal cancer patients who received bevacizumab treatment, non-small cell lung cancer patients under bevacizumab treatment caused more adverse reactions. Among 100 colorectal cancer patients, the number of patients with bevacizumab-related hypertension in grade 1, grade 2 and grade 3 were 45, 12 and 23 respectively. Among 100 non-small cell lung cancer patients, the number of patients with bevacizumab-related hypertension in grade 1, grade 2 and grade 3 were 44, 25 and 20 respectively. Bevacizumab-related hypertension can improve the prognosis and efficacy of colorectal cancer and non-small cell lung cancer patients.
引用
收藏
页码:21 / 24
页数:4
相关论文
共 50 条
  • [41] MONOTOTAL - PROGNOSIS AND THERAPY CONTROL IN PATIENTS WITH NON-SMALL CELL LUNG CANCER
    Fuchsova, R.
    Topolcan, O.
    Krakorova, G.
    Prazakova, M.
    Svobodova, S.
    Holubec, L.
    Safranek, J.
    Vrzalova, J.
    Casova, M.
    Treska, V
    Treskova, I
    Pesek, M.
    Finek, J.
    CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2011, 49 : S279 - S279
  • [42] Bevacizumab for the treatment of non-small cell lung cancer patients with synchronous brain metastases
    Mustafa S. Ascha
    Jacqueline Fang Wang
    Priya Kumthekar
    Andrew E. Sloan
    Carol Kruchko
    Jill S. Barnholtz-Sloan
    Scientific Reports, 9
  • [43] Bevacizumab for the treatment of non-small cell lung cancer patients with synchronous brain metastases
    Ascha, Mustafa S.
    Wang, Jacqueline Fang
    Kumthekar, Priya
    Sloan, Andrew E.
    Kruchko, Carol
    Barnholtz-Sloan, Jill S.
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [44] How Should We Use Bevacizumab in Patients with Non-small Cell Lung Cancer?
    Kim, Young Hak
    Mishima, Michiaki
    JOURNAL OF THORACIC ONCOLOGY, 2011, 6 (12) : 2145 - 2146
  • [45] Safety and efficacy of bevacizumab in "fragile" patients with advanced non-small cell lung cancer
    Maragkos, C.
    Grapsa, D.
    Koumakis, G.
    Polyzos, A.
    Syrigos, K.
    ANNALS OF ONCOLOGY, 2017, 28
  • [46] ASSESSING THE UTILIZATION OF DIABETIC NON-SMALL CELL LUNG CANCER PATIENTS COMPARED TO NON-SMALL CELL LUNG CANCER PATIENTS
    Ruban, C.
    Blanchette, C. M.
    Howden, R.
    Kowalkowski, M.
    Marino, J.
    Saunders, W.
    VALUE IN HEALTH, 2017, 20 (09) : A511 - A511
  • [47] Clinical factors and prognosis in non-small cell lung cancer
    Martins, SJ
    Pereira, JR
    AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 1999, 22 (05): : 453 - 457
  • [48] Protein signature for non-small cell lung cancer prognosis
    Liu, Wei
    Wu, Yong
    Wang, Libo
    Gao, Ling
    Wang, Yingping
    Liu, Xiaoliang
    Zhang, Kai
    Song, Jena
    Wang, Hongxia
    Bayer, Thomas A.
    Glaser, Laurel
    Sun, Yezhou
    Zhang, Weijia
    Cutaia, Michael
    Zhang, David Y.
    Ye, Fei
    AMERICAN JOURNAL OF CANCER RESEARCH, 2014, 4 (03): : 256 - U237
  • [49] PROTEIN SIGNATURE FOR NON-SMALL CELL LUNG CANCER PROGNOSIS
    Cui, Miao
    Liu, Wei
    Zhang, David
    JOURNAL OF THORACIC ONCOLOGY, 2012, 7 (07) : S132 - S132
  • [50] Multimodal learning for non-small cell lung cancer prognosis
    Wu, Yujiao
    Wang, Yaxiong
    Huang, Xiaoshui
    Wang, Haofei
    Yang, Fan
    Sun, Wenwen
    Su, Steven W.
    Ling, Sai Ho
    BIOMEDICAL SIGNAL PROCESSING AND CONTROL, 2025, 106