Recent Insights into the Pathophysiology of Omental Metastases

被引:36
|
作者
Koppe, Manuel J. [1 ,2 ]
Nagtegaal, Iris D. [3 ]
de Wilt, Johannes H. W. [1 ]
Ceelen, Wim P. [2 ]
机构
[1] Radboud Univ Nijmegen, Dept Surg, Med Ctr, NL-6500 HB Nijmegen, Netherlands
[2] Ghent Univ Hosp, Dept Surg, Ghent, Belgium
[3] Radboud Univ Nijmegen, Dept Pathol, Med Ctr, NL-6500 HB Nijmegen, Netherlands
关键词
omental metastases; pathophysiology; milky spots; adipose stem cells; adipocytes; HUMAN GREATER OMENTUM; MILKY SPOTS; PERITONEAL CARCINOMATOSIS; OVARIAN-CANCER; COLORECTAL ORIGIN; OMENTECTOMY; ADIPOSE; GROWTH; CELLS; CHEMOTHERAPY;
D O I
10.1002/jso.23681
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Although, useful in inflammatory conditions, the greater omentum represents an important site of metastasis in peritoneal carcinomatosis and is therefore frequently removed as a staging or therapeutic tool. Apart from the milky spots, omental adipose stem cells, and adipocytes have recently been identified to play a role in the preferential homing of tumor cells to the omentum. The extent of omentectomy and whether a routine omentectomy should be done are still known unknowns. J. Surg. Oncol. 2014 110:670-675. (c) 2014 Wiley Periodicals, Inc.
引用
收藏
页码:670 / 675
页数:6
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