Population genetics of Y chromosomal STR haplotypes in Japanese population

被引：0

作者：

Hashimoto, C ^{[1
]}

Nakamura, S ^{[1
]}

Sasaki, C ^{[1
]}

Takeshita, H ^{[1
]}

Nagai, T ^{[1
]}

Sugie, H ^{[1
]}

Furukawa, M ^{[1
]}

Kurihara, K ^{[1
]}

机构：

[1] Kitasato Univ, Sch Med, Dept Legal Med, Sagamihara, Kanagawa 2288555, Japan

来源：

PROGRESS IN FORENSIC GENETICS 10 | 2004年 / 1261卷

关键词：

Y chromosome; STR; gene diversity; haplotype diversity; Japanese population;

D O I：

10.1016/S0531-5131(03)01703-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Five Y chromosomal short tandem repeat (STR) loci DYS389I DYS389II, DYS439, DYS438 and DYS392 have been analysed to obtain the allele and haplotype frequencies data in 129 unrelated Japanese male individuals living in Kanagawa by means of multiplex PCR with Y-LEX(TM) 5 Primer Mix, followed by capillary electrophoresis using the ABI PRISM 310 Genetic Analyzer. The gene diversity values ranged from 0.555 (DYS439) to 0.737 (DYS389II). A total of 72 haplotypes was detected, of which 51 haplotypes were unique and the others occurred at least two times. The most common haplotype (DYS389I, DYS389II, DYS439, DYS438, DYS392) was 14-30-12-13-13 with a frequency of 10%, and the haplotype diversity was calculated as 0.969. The combined resolutions of the 5 Y STR multiplex system using the Y-PLEX(TM) 5 was applicable to routine case work. (C) 2003 Elsevier B.V. All rights reserved.

引用

页码：313 / 315

页数：3

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