Increased extracellular matrix stiffness has long been associated with malignant transformation in breast cancer. Now, Stowers et al. have shown that matrix stiffness induces a tumorigenic phenotype by affecting the epigenetic landscape of a cell.
机构:
Stanford Univ, Steyer Taylor Ctr Energy Policy & Finance, Stanford, CA 94305 USAStanford Univ, Steyer Taylor Ctr Energy Policy & Finance, Stanford, CA 94305 USA