Selective inhibitors of GSK-3β: a suitable therapy for Down syndrome?

被引：1
|
作者：
Giacomini, A. [1 ]
Stagni, F. [1 ]
Emili, M. [1 ]
Guidi, S. [1 ]
Salvalai, M. E. [2 ]
Vidal-Sanchez, V. [3 ]
Grilli, M. [2 ]
Martinez-Cue Pesini, C. [3 ]
Bartesaghi, R. [1 ]
机构：
[1] Univ Bologna, Dept Biomed & Neuromotor Sci, Bologna, Italy
[2] Amedeo Avogadro Univ Eastern Piedmont, Dept Pharmaceut Sci, Novara, Italy
[3] Univ Cantabria, Dept Physiol & Pharmacol, Santander, Spain
来源：
EUROPEAN NEUROPSYCHOPHARMACOLOGY | 2018年 / 28卷
关键词：
NEUROGENESIS;
D O I：
10.1016/j.euroneuro.2017.12.105
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
P.3.015
引用
收藏
页码：S72 / S73
页数：2
相关论文
共 50 条
  • [31] Biological evaluation and energetic analyses of novel GSK-3β inhibitors
    Zhang, Denan
    Liu, Lei
    Pang, Lin
    Jin, Qing
    Ke, Kehui
    Hu, Ming
    Yang, Jingbo
    Ma, Weifang
    Xie, Hongbo
    Chen, Xiujie
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2018, 119 (04) : 3510 - 3518
  • [32] 5-Aryl-4-carboxamide-1,3-oxazoles: Potent and selective GSK-3 inhibitors
    Gentile, Gabriella
    Merlo, Giancarlo
    Pozzan, Alfonso
    Bernasconi, Giovanni
    Bax, Benjamin
    Bamborough, Paul
    Bridges, Angela
    Carter, Paul
    Neu, Margarete
    Yao, Gang
    Brough, Caroline
    Cutler, Geoffrey
    Coffin, Aaron
    Belyanskaya, Svetlana
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 22 (05) : 1989 - 1994
  • [33] Structural assessment for active and selective kinase inhibitors: GSK-3β and CDK2 case studies
    Elokely, Khaled M.
    Fu, Gang
    Doerksen, Robert J.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 245
  • [34] Fragment and knowledge-based design of selective GSK-3β inhibitors using virtual screening models
    Vadivelan, S.
    Sinha, Barij Nayan
    Tajne, Sunita
    Jagarlapudi, Sarma A. R. P.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 44 (06) : 2361 - 2371
  • [35] Novel GSK-3β inhibitors from sequential virtual screening
    Kim, Hye-Jung
    Choo, Hyunah
    Cho, Yong Seo
    No, Kyoung Tal
    Pae, Ae Nim
    BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 16 (02) : 636 - 643
  • [36] GSK-3α/β and MEK inhibitors assist the microenvironment of tumor initiation
    Ghmkin Hassan
    Said M. Afify
    Maram H. Zahra
    Hend M. Nawara
    Kazuki Kumon
    Yoshiaki Iwasaki
    David S. Salomon
    Akimasa Seno
    Masaharu Seno
    Cytotechnology, 2023, 75 : 243 - 253
  • [37] GSK-3α/β and MEK inhibitors assist the microenvironment of tumor initiation
    Hassan, Ghmkin
    Afify, Said M.
    Zahra, Maram H.
    Nawara, Hend M.
    Kumon, Kazuki
    Iwasaki, Yoshiaki
    Salomon, David S.
    Seno, Akimasa
    Seno, Masaharu
    CYTOTECHNOLOGY, 2023, 75 (03) : 243 - 253
  • [38] MEK and GSK-3 inhibitors enhance the microenvironment of tumor initiation
    Ghmkin, Hassan
    Afify, Said M.
    Zahara, Maram H.
    Salomon, David S.
    Seno, Akimasa
    Seno, Masaharu
    CANCER SCIENCE, 2022, 113 : 1326 - 1326
  • [39] GSK-3 Inhibitors: From the Brain to the Retina and Back Again
    Sanchez-Cruz, Alonso
    Martinez, Ana
    de la Rosa, Enrique J.
    Hernandez-Sanchez, Catalina
    RETINAL DEGENERATIVE DISEASES: MECHANISMS AND EXPERIMENTAL THERAPY, 2019, 1185 : 437 - 441
  • [40] A NEW CLASS OF MOLECULAR TARGETED RADIOPROTECTORS: GSK-3β INHIBITORS
    Thotala, Dinesh K.
    Geng, Ling
    Dickey, Amy K.
    Hallahan, Dennis E.
    Yazlovitskaya, Eugenia M.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2010, 76 (02): : 557 - 565
12345