Studies on changes in trace elemental content of serum of uterine cervix cancer patients using PIXE

被引：2
|
作者：
Sarita, P. [1 ]
Raju, G. J. Naga [2 ]
Reddy, S. Bhuloka [3 ]
机构：
[1] GITAM Univ, GIT, Dept Phys, Visakhapatnam 530045, Andhra Pradesh, India
[2] JNTUK, UCEV, Dept Phys, Vizianagaram 535003, India
[3] Andhra Univ, Swami Jnanananda Labs Nucl Res, Visakahpatnam 530003, India
来源：
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY | 2014年 / 302卷 / 03期
关键词：
PIXE; Trace elements; Uterine cervix cancer; OXIDATIVE DNA-DAMAGE; NF-KAPPA-B; SOFTWARE PACKAGE; ZINC-DEFICIENCY; SELENIUM; COPPER; CELLS; REPAIR; RAT; P53;
D O I：
10.1007/s10967-014-3591-2
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The objective of this study was to evaluate the levels of trace elements in blood sera of uterine cervix cancer patients, analyze their alteration with respect to healthy controls and identify the best predictors amongst these for disease occurrence and progression. Particle induced X-ray emission (PIXE) technique was used in this work to identify and quantify trace elements Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Br in the blood sera of uterine cervix cancer subjects and healthy control subjects. The observed alterations are discussed with respect to the possible mechanisms by which these elements might influence the carcinogenic process.
引用
收藏
页码：1501 / 1506
页数：6
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