A novel candidate gene to rescue misprocessing of ΔF508 CFTR present in most patients with cystic fibrosis

被引:0
|
作者
Okiyoneda, T
Jono, H
Wada, I
Shuto, T
Yoshitake, K
Shibata, Y
Nagayama, S
Riordan, JR
Isohama, Y
Miyata, T
Kai, H
机构
[1] Kumamoto Univ, Kumamoto 8620973, Japan
[2] Sapporo Med Coll, Sapporo, Hokkaido, Japan
[3] Mayo Clin Scottsdale, Johnson Med Res Ctr, Scottsdale, AZ 85251 USA
关键词
D O I
暂无
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
2175
引用
收藏
页码:419A / 419A
页数:1
相关论文
共 50 条
  • [31] Organic solutes rescue the functional defect in ΔF508 cystic fibrosis transmembrane conductance regulator
    Zhang, XM
    Wang, XT
    Yue, HW
    Leung, SW
    Thibodeau, PH
    Thomas, PJ
    Guggino, SE
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (51) : 51232 - 51242
  • [32] FREQUENCY OF THE F508-DELETION IN THE CFTR GENE IN TURKISH CYSTIC-FIBROSIS PATIENTS
    HUNDRIESER, J
    BREMER, S
    PEINEMANN, F
    STUHRMANN, M
    HOFFKNECHT, N
    WULF, B
    SCHMIDTKE, J
    REISS, J
    MAASS, G
    TUMMLER, B
    HUMAN GENETICS, 1990, 85 (04) : 409 - 410
  • [33] Mild processing defect of porcine ΔF508-CFTR suggests that ΔF508 pigs may not develop cystic fibrosis disease
    Liu, Yanli
    Wang, Ying
    Jiang, Yong
    Zhu, Na
    Liang, Haitao
    Xu, Lina
    Feng, Xuechao
    Yang, Hong
    Ma, Tonghui
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 373 (01) : 113 - 118
  • [34] Genetic modification of cystic fibrosis with ΔF508 mutation of CFTR gene using the CRISPR system in peripheral blood mononuclear cells
    Khatibi, Sepideh
    Modaresi, Mohammadreza
    Oskuee, Reza Kazemi
    Salehi, Mohammad
    Aghaee-Bakhtiari, Seyed Hamid
    IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021, 24 (02) : 73 - 78
  • [35] Calpain Inhibition Promotes the Rescue of F508del-CFTR in PBMC from Cystic Fibrosis Patients
    Averna, Monica
    Pedrazzi, Marco
    Minicucci, Laura
    De Tullio, Roberta
    Cresta, Federico
    Salamino, Franca
    Pontremoli, Sandro
    Melloni, Edon
    PLOS ONE, 2013, 8 (06):
  • [36] Cystic fibrosis gene mutations Δf508 and 394delTT in patients with chronic sinusitis in Finland
    Hytönen, M
    Patjas, M
    Vento, SI
    Kauppi, P
    Malmberg, H
    Ylikoski, J
    Kere, J
    ACTA OTO-LARYNGOLOGICA, 2001, 121 (08) : 945 - 947
  • [37] Preimplantation genetic diagnosis of cystic fibrosis (Delta F508)
    Ao, A
    Handyside, A
    Winston, RML
    EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 1996, 65 (01): : 7 - 10
  • [38] Evidence against resveratrol as a viable therapy for the rescue of defective ΔF508 CFTR
    Jai, Ying
    Shah, Kalpit
    Bridges, Robert J.
    Bradbury, Neil A.
    BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2015, 1850 (11): : 2377 - 2384
  • [39] NOVEL SMALL MOLECULE CORRECTORS AND POTENTIATORS OF ΔF508 CFTR
    Pregel, M.
    DeVit, M.
    Fleming, J.
    Elbaum, D.
    Balch, W.
    Pedemonte, N.
    Galietta, L. J.
    Rutkowski, J.
    Weigel, C.
    DesRosiers, R.
    Liang, F.
    Eskin, J.
    Li, C.
    Bulawa, C.
    Labaudiniere, R.
    PEDIATRIC PULMONOLOGY, 2009, : 287 - 288
  • [40] Constrained bithiazoles as correctors for the ΔF508 cystic fibrosis transmembrane conductance regulator gene
    Coffman, Keith C.
    Nguyen, Huy H.
    Phuan, Puay-Wah
    Yu, Gui J.
    Bagdasarian, Alex L.
    Montgomery, Deanna
    Lodewyk, Michael W.
    Yang, Baoxue
    Yoo, Choong L.
    Verkman, Alan S.
    Tantillo, Dean J.
    Kurth, Mark J.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 248