Dynamic modulation of rTMS on functional connectivity and functional network connectivity to children with cerebral palsy: a case report

被引:13
|
作者
Guo, Zhiwei [1 ,2 ]
Xing, Guoqiang [5 ]
He, Bin [1 ,2 ]
Chen, Huaping [1 ,2 ]
Ou, Jun [1 ,2 ]
McClure, Morgan A. [1 ,2 ]
Liu, Hua [3 ]
Wang, Yunfeng [3 ]
Mu, Qiwen [1 ,2 ,4 ]
机构
[1] North Sichuan Med Univ, Nanchong Cent Hosp, Dept Radiol, 97 South Renmin Rd, Nanchong 637000, Sichuan, Peoples R China
[2] North Sichuan Med Univ, Nanchong Cent Hosp, Imaging Inst Rehabil & Dev Brain Funct, 97 South Renmin Rd, Nanchong 637000, Sichuan, Peoples R China
[3] North Sichuan Med Univ, Nanchong Cent Hosp, Dept Neurol, Nanchong, Sichuan, Peoples R China
[4] Peking Univ, Dept Radiol, Hosp 3, Beijing 100871, Peoples R China
[5] Johns Hopkins Univ, Lotus Biotech Com LLC, MCC, Rockville, MD USA
关键词
cerebral palsy; functional connectivity; functional MRI; functional network connectivity; repetitive transcranial magnetic stimulation; TRANSCRANIAL MAGNETIC STIMULATION; ATTENTION; YOUTH;
D O I
10.1097/WNR.0000000000000534
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive treatment tool for the recovery of cerebral palsy (CP). This report describes the modulation effect of rTMS to functional connectivity, functional network connectivity, motor, and cognitive ability following treatment in a child with mild ataxia CP. After receiving 8 months of 0.5Hz rTMS treatment over the right dorsolateral prefrontal cortex, the child showed a gradual improvement in motor and cognitive-related functional connectivity and functional network connectivity following treatment as well as improved motor, cognitive functions. These pilot results provide the first evidence of the efficiency of 0.5Hz of rTMS on a child with CP. Further large sample studies are needed to verify and expand the present findings. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.
引用
收藏
页码:284 / 288
页数:5
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