Photoacoustic temperature imaging based on multi-wavelength excitation

被引:29
|
作者
Meng, Lei [1 ]
Deschaume, Olivier [1 ]
Larbanoix, Lionel [2 ]
Fron, Eduard [3 ]
Bartic, Carmen [1 ]
Laurent, Sophie [2 ]
Van der Auweraer, Mark [3 ]
Glorieux, Christ [1 ]
机构
[1] Katholieke Univ Leuven, Dept Phys & Astron, Soft Matter & Biophys, Celestijnenlaan 200D Box 2416, B-3001 Leuven, Belgium
[2] Ctr Microscopy & Mol Imaging, Rue Adrienne Bolland 8, B-6041 Gosselies, Belgium
[3] Katholieke Univ Leuven, Dept Chem, Mol Imaging & Photon, Celestijnenlaan 200F Box 2404, B-3001 Leuven, Belgium
来源
PHOTOACOUSTICS | 2019年 / 13卷
关键词
Photoacoustic imaging; Multispectral optoacoustic tomography; Absorption coefficient; Finite difference; REAL-TIME; TOMOGRAPHY; NANOPARTICLES; THERMOGRAPHY; THERAPY; AGENTS;
D O I
10.1016/j.pacs.2018.11.004
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
Building further upon the high spatial resolution offered by ultrasonic imaging and the high optical contrast yielded by laser excitation of photoacoustic imaging, and exploiting the temperature dependence of photoacoustic signal amplitudes, this paper addresses the question whether the rich information given by multispectral optoacoustic tomography (MSOT) allows to obtain 3D temperature images. Numerical simulations and experimental results are reported on agarose phantoms containing gold nanoparticles and the effects of shadowing, reconstruction flaws, etc. on the accuracy are determined.
引用
收藏
页码:33 / 45
页数:13
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