Principles of molecular genetics and cellular biology in the origin of malignant tumors

被引:0
|
作者
Kassen, A [1 ]
Hofmockel, G [1 ]
机构
[1] Ruhr Univ Bochum, Urol Klin, Marien Hosp Herne, Bochum, Germany
来源
UROLOGE A | 2000年 / 39卷 / 03期
关键词
multi-step carcinogenesis; cell cycle; proto-oncogene; tumor suppressor gene; DNA repair gene; apoptosis; telomeres;
D O I
10.1007/s001200050344
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
most intensively studied areas of medical research resulting in an immense quantity of data. Therefore, the purpose of this article is to give an overview of the basic principles of cancer development. Key words such as multi-step carcinogenesis, cell cycle, protooncogene, tumor suppressor gene, DNA repair gene, apoptosis and telomeres are explained and described in examples. This paper aims to connect recent information of molecular and cellular biology in an overview of cancer origin and development.
引用
收藏
页码:214 / 221
页数:8
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