Teaching molecular genetics: Chapter 1 - Background principles and methods of molecular biology

被引：3
|
作者：
Knoers, NVAM
Monnens, LAH
机构：
[1] Univ Med Ctr Nijmegen, Dept Human Genet, NL-6500 HB Nijmegen, Netherlands
[2] Univ Med Ctr Nijmegen, Dept Paediat Nephrol, Nijmegen, Netherlands
来源：
PEDIATRIC NEPHROLOGY | 2006年 / 21卷 / 02期
关键词：
Bacterial Artificial Chromosome; Yeast Artificial Chromosome; Triplet Codon; Correct Amino Acid; Splice Consensus Sequence;
D O I：
10.1007/s00467-005-2154-8
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
In this first chapter of the series "Teaching molecular genetics," an introduction to molecular genetics is presented. We describe the structure of DNA and genes and explain in detail the central dogma of molecular biology, that is, the flow of genetic information from DNA via RNA to polypeptide (protein). In addition, several basic and frequently used general molecular tools, such as restriction enzymes, Southern blotting, DNA amplification and sequencing are discussed, in order to lay the foundations for the forthcoming chapters.
引用
收藏
页码：169 / 176
页数：8
相关论文
共 50 条
  • [1] Teaching molecular genetics: Chapter 1—Background principles and methods of molecular biology
    Nine V. A. M. Knoers
    Leo A. H. Monnens
    Pediatric Nephrology, 2006, 21 : 169 - 176
  • [2] Teaching molecular genetics: Chapter 3 – Proteomics in nephrology
    Patricia J. T. A. Groenen
    Lambert P. W. J. van den Heuvel
    Pediatric Nephrology, 2006, 21 : 611 - 618
  • [3] Teaching molecular genetics: Chapter 3 - Proteomics in nephrology
    Groenen, PJTA
    van den Heuvel, LPWJ
    PEDIATRIC NEPHROLOGY, 2006, 21 (05) : 611 - 618
  • [4] Primer on medical genomics part II: Background principles and methods in molecular genetics
    Tefferi, A
    Wieben, ED
    Dewald, GW
    Whiteman, DAH
    Bernard, ME
    Spelsberg, TC
    MAYO CLINIC PROCEEDINGS, 2002, 77 (08) : 785 - 804
  • [5] Methods in molecular biology and genetics: looking to the future
    Forero, Diego A.
    Chand, Vaibhav
    BMC RESEARCH NOTES, 2023, 16 (01)
  • [6] Methods in molecular biology and genetics: looking to the future
    Diego A. Forero
    Vaibhav Chand
    BMC Research Notes, 16
  • [7] Teaching molecular genetics: chapter 4—positional cloning of genetic disorders
    Aldamaria Puliti
    Gianluca Caridi
    Roberto Ravazzolo
    Gian Marco Ghiggeri
    Pediatric Nephrology, 2007, 22 : 2023 - 2029
  • [8] LYSOZYMES - A CHAPTER OF MOLECULAR BIOLOGY
    JOLLES, P
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1969, 8 (04) : 227 - &
  • [9] Effective teaching methods for Systems and Molecular Biology
    Pritchard, J.
    PHOTOSYNTHESIS RESEARCH, 2007, 91 (2-3) : 323 - 323
  • [10] Principles of molecular genetics and cellular biology in the origin of malignant tumors
    Kassen, A
    Hofmockel, G
    UROLOGE A, 2000, 39 (03): : 214 - 221
12345