Alkylation of aldehyde (arenesulfonyl) hydrazones with trialkylboranes

被引：25

作者：

Kabalka, GW ^{[1
]}

Maddox, JT ^{[1
]}

Bogas, E ^{[1
]}

Kelley, SW ^{[1
]}

机构：

[1] UNIV TENNESSEE,DEPT RADIOL,KNOXVILLE,TN 37996

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1997年 / 62卷 / 11期

关键词：

D O I：

10.1021/jo962089q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(Arenesulfonyl)hydrazone derivatives of aryl aldehydes are readily alkylated by trialkylboranes in the presence of base to generate new organoboranes that may be converted to the corresponding substituted alkanes or alcohols depending upon the reaction conditions chosen. Both tosyl- and trisylhydrazone derivatives can be utilized in the reaction, which tolerates a variety of functional groups, making it a versatile alternative to both the Grignard and Suzuki-coupling reactions.

引用

页码：3688 / 3695

页数：8

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