Mechanistic Studies of PD-1 Signaling in the Conversion of Effector T Cells to Functional Exhaustion

被引:0
|
作者
Prosser, Megan E. [1 ]
Jensen, Michael C. [1 ]
Rossi, John J. [1 ]
机构
[1] City Hope Natl Med Ctr, Beckman Res Inst, Div Canc Immunotherapeut & Tumor Immunol, Duarte, CA 91010 USA
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:S216 / S216
页数:1
相关论文
共 50 条
  • [21] PD-1 signaling uncovers a pathogenic subset of T cells in inflammatory arthritis
    Straube, Johanna
    Bukhari, Shoiab
    Lerrer, Shalom
    Winchester, Robert J.
    Gartshteyn, Yevgeniya
    Henick, Brian S.
    Dragovich, Matthew A.
    Mor, Adam
    ARTHRITIS RESEARCH & THERAPY, 2024, 26 (01)
  • [22] PD-1 signaling uncovers a pathogenic subset of T cells in inflammatory arthritis
    Johanna Straube
    Shoiab Bukhari
    Shalom Lerrer
    Robert J. Winchester
    Yevgeniya Gartshteyn
    Brian S. Henick
    Matthew A. Dragovich
    Adam Mor
    Arthritis Research & Therapy, 26
  • [23] Negative regulation of T cells: reconstitution and visualization of the PD-1 signaling pathway
    Hui, E.
    Zhu, J.
    Cheung, J.
    Su, X.
    Taylor, M. J.
    Kim, J. M.
    Mellman, I.
    Vale, R. D.
    MOLECULAR BIOLOGY OF THE CELL, 2015, 26
  • [24] Inhibition of the PD-1 pathway restores the effector function of HIV-specific T cells
    Trautmann, Lydie
    Chomont, Nicolas
    Sekaly, Rafick-Pierre
    M S-MEDECINE SCIENCES, 2007, 23 (01): : 24 - 25
  • [25] PD-L1/PD-1 Immunotherapy Modulates Effector T Cells Homeostasis and Function in Murine Pancreatic Cancer
    Rivera, Ivannie Ortiz
    Iclozan, Cristina
    McGill, Andrew
    Ghansah, Tomar
    JOURNAL OF IMMUNOLOGY, 2016, 196
  • [26] PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
    Day, Cheryl L.
    Kaufmann, Daniel E.
    Kiepiela, Photini
    Brown, Julia A.
    Moodley, Eshia S.
    Reddy, Sharon
    Mackey, Elizabeth W.
    Miller, Joseph D.
    Leslie, Alasdair J.
    DePierres, Chantal
    Mncube, Zenele
    Duraiswamy, Jaikumar
    Zhu, Baogong
    Eichbaum, Quentin
    Altfeld, Marcus
    Wherry, E. John
    Coovadia, Hoosen M.
    Goulder, Philip J. R.
    Klenerman, Paul
    Ahmed, Rafi
    Freeman, Gordon J.
    Walker, Bruce D.
    NATURE, 2006, 443 (7109) : 350 - 354
  • [27] PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
    Cheryl L. Day
    Daniel E. Kaufmann
    Photini Kiepiela
    Julia A. Brown
    Eshia S. Moodley
    Sharon Reddy
    Elizabeth W. Mackey
    Joseph D. Miller
    Alasdair J. Leslie
    Chantal DePierres
    Zenele Mncube
    Jaikumar Duraiswamy
    Baogong Zhu
    Quentin Eichbaum
    Marcus Altfeld
    E. John Wherry
    Hoosen M. Coovadia
    Philip J. R. Goulder
    Paul Klenerman
    Rafi Ahmed
    Gordon J. Freeman
    Bruce D. Walker
    Nature, 2006, 443 : 350 - 354
  • [28] Identification of the functional PD-L1 interface region responsible for PD-1 binding and initiation of PD-1 signaling
    Carter, Rachel
    Alanazi, Fatimah
    Sharp, Amanda
    Roman, Jessica
    Luchini, Alessandra
    Liotta, Lance
    Paige, Mikell
    Brown, Anne M.
    Haymond, Amanda
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 299 (12)
  • [29] Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells
    Zhao, Yunlong
    Harrison, Devin L.
    Song, Yuran
    Ji, Jie
    Huang, Jun
    Hui, Enfu
    CELL REPORTS, 2018, 24 (02): : 379 - +
  • [30] PD-1 and LAG-3: synergistic fostering of T cell exhaustion
    Hofmann, Maike
    Thimme, Robert
    Schamel, Wolfgang W.
    SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 9 (01)