Signet-ring cell carcinoma of the duodenal bulb presenting with gastrointestinal hemorrhage: a case report and literature review

被引:3
|
作者
Ye, Nan [1 ]
Bao, Xiaoxiao [2 ]
Zhao, Xiaokang [3 ]
Wang, Bin [1 ]
机构
[1] Dongyang Peoples Hosp, Dept Hepatobiliary Surg, Jinhua 322100, Zhejiang, Peoples R China
[2] Dongyang Peoples Hosp, Dept Pathol, Jinhua 322100, Zhejiang, Peoples R China
[3] Dongyang Peoples Hosp, Dept Gastrointestinal Surg, Jinhua 322100, Zhejiang, Peoples R China
关键词
Duodenal; Bulb; Signet-ring cell carcinoma; CLINICOPATHOLOGICAL ANALYSIS; PROGNOSTIC-FACTORS; ADENOCARCINOMA; AMPULLARY; CHEMOTHERAPY; IMPACT;
D O I
10.1186/s12876-022-02267-0
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background Primary duodenal cancer (PDC) is rare, especially signet-ring cell carcinoma (SRCC) of the duodenal bulb, and it is commonly misdiagnosed as an ulceration. Here, we report a rare case of SRCC of the duodenal bulb presenting with gastrointestinal hemorrhage in an 82-year-old man. Case presentation An 82-year-old man was admitted for gastrointestinal hemorrhage. Physical examination revealed upper abdominal tenderness and pale appearance, but was otherwise unrevealing. Laboratory workup was significant for anemia. Imaging showed no abnormalities. Two endoscopic evaluations along with interventional embolization were attempted and, unfortunately, adequate hemostasis was not achieved, resulting in distal subtotal gastrectomy, including the duodenal bulb. SRCC of the duodenal bulb was diagnosed based on pathology after surgery. Post-operatively, the patient experienced persistent gastrointestinal bleeding. Family declined further intervention and the patient eventually died one month post-resection. Conclusions SRCC in the duodenal bulb is difficult to diagnose. For those with high-risk factors, endoscopic examination and biopsy are recommended. For patients who can receive radical tumor resection, pancreaticoduodenectomy (PD) is considered a first-line option. Early diagnosis and resection have been shown to improve prognosis.
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页数:6
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