Protein Kinase C/Mitogen-Activated Protein Kinase Signaling in Keratinocyte Differentiation control

被引：9
|
作者：
Denning, Mitchell F. [1 ,2 ]
机构：
[1] Loyola Univ, Skin Canc Res Program, Dept Pathol, Maywood, IL 60153 USA
[2] Loyola Univ, Skin Canc Res Program, Cardinal Bernardin Canc Ctr, Maywood, IL 60153 USA
来源：
JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2010年 / 130卷 / 08期
关键词：
INVOLUCRIN GENE; C-DELTA; FILAGGRIN;
D O I：
10.1038/jid.2010.194
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Proper epidermal keratinocyte differentiation, which is necessary for cutaneous barrier function, is altered in many common skin diseases. Keratinocyte differentiation is controlled by a complex signaling network involving multiple members of the protein kinase c and mitogen-activated protein kinase signaling kinases. Using an RNA interference knockdown approach, Adhikary et al. identified essential nodes in this signaling network, revealing remarkable kinase specificity.
引用
收藏
页码：1968 / 1970
页数：4
相关论文
共 50 条
  • [1] Mitogen-activated protein kinase signaling
    Kyosseva, SV
    DISORDERS OF SYNAPTIC PLASTICITY AND SCHIZOPHRENIA, 2004, 59 : 201 - +
  • [2] Dual role of protein kinase C on mitogen-activated protein kinase activation and human keratinocyte proliferation
    Praskova, M
    Kalenderova, S
    Miteva, L
    Poumay, Y
    Mitev, V
    EXPERIMENTAL DERMATOLOGY, 2002, 11 (04) : 344 - 348
  • [3] Cilia and mitogen-activated protein kinase signaling
    Jivan, Arif
    Earnest, Svetlana
    Cobb, Melanie H.
    FASEB JOURNAL, 2008, 22
  • [4] Mitogen-Activated Protein Kinase Signaling in Plants
    Rodriguez, Maria Cristina Suarez
    Petersen, Morten
    Mundy, John
    ANNUAL REVIEW OF PLANT BIOLOGY, VOL 61, 2010, 61 : 621 - 649
  • [5] Control of the Osteoblast Lineage by Mitogen-Activated Protein Kinase Signaling
    Renny T. Franceschi
    Chunxi Ge
    Current Molecular Biology Reports, 2017, 3 (2) : 122 - 132
  • [6] Protein kinase C regulates chondrogenesis of mesenchymes via mitogen-activated protein kinase signaling
    Chang, SH
    Oh, CD
    Yang, MS
    Kang, SS
    Lee, YS
    Sonn, JK
    Chun, JS
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (30) : 19213 - 19219
  • [7] Protein kinase C and mitogen-activated protein kinase signalling in oligodendrocytes
    Stariha, RL
    Kim, SU
    MICROSCOPY RESEARCH AND TECHNIQUE, 2001, 52 (06) : 680 - 688
  • [8] The mitogen-activated protein kinase signaling pathways: role in megakaryocyte differentiation
    Severin, S.
    Ghevaert, C.
    Mazharian, A.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2010, 8 (01) : 17 - 26
  • [9] Regulation of mitogen-activated protein kinase by protein kinase C and mitogen-activated protein kinase phosphatase-1 in vascular smooth muscle
    Trappanese, Danielle M.
    Sivilich, Sarah
    Ets, Hillevi K.
    Kako, Farah
    Autieri, Michael V.
    Moreland, Robert S.
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2016, 310 (11): : C921 - C930
  • [10] Keratinocyte survival, differentiation, and death: Many roads lead to mitogen-activated protein kinase
    Eckert, RL
    Efimova, T
    Dashti, SR
    Balasubramanian, S
    Deucher, A
    Crish, JF
    Sturniolo, M
    Bone, F
    JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS, 2002, 7 (01) : 36 - 40
12345