BioSamplr: An open source, low cost automated sampling system for bioreactors

被引：4
|
作者：
Efromson, John P. [1 ]
Li, Shuai [2 ]
Lynch, Michael D. [1 ]
机构：
[1] Duke Univ, Dept Biomed Engn, Durham, NC 27706 USA
[2] Duke Univ, Dept Chem, Durham, NC 27706 USA
来源：
HARDWAREX | 2021年 / 9卷
关键词：
Liquid-handling; Fermentation; Bioengineering; Automation;
D O I：
10.1016/j.ohx.2021.e00177
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
Autosampling from bioreactors reduces error, increases reproducibility and offers improved aseptic handling when compared to manual sampling. Additionally, autosampling greatly decreases the hands-on time required for a bioreactor experiment and enables sampling 24 h a day. We have designed, built and tested a low cost, open source, automated bioreactor sampling system, the BioSamplr. The BioSamplr can take up to ten samples from a bioreactor at a desired sample interval and cools them to a desired temperature. The device, assembled from low cost and 3D printed components, is controlled wirelessly by a Raspberry Pi, and records all sampling data to a log file. The cost and accessibility of the BioSamplr make it useful for laboratories without access to more expensive and complex autosampling systems. (C) 2021 The Author(s). Published by Elsevier Ltd.
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页数：10
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