International Society of Urological Pathology (ISUP) grading of prostate cancer - An ISUP consensus on contemporary grading

被引：166
|
作者：
Egevad, Lars [1 ,2 ]
Delahunt, Brett [3 ]
Srigley, John R. [4 ]
Samaratunga, Hemamali [5 ,6 ]
机构：
[1] Karolinska Inst, Dept Pathol & Oncol, Stockholm, Sweden
[2] Karolinska Univ Hosp, Dept Pathol, Stockholm, Sweden
[3] Univ Otago, Dept Pathol & Mol Med, Wellington Sch Med & Hlth Sci, Wellington, New Zealand
[4] McMaster Univ, Dept Pathol & Mol Med, Hamilton, ON, Canada
[5] Aquesta Pathol, Brisbane, Qld, Australia
[6] Univ Queensland, Sch Med, Brisbane, Qld, Australia
来源：
APMIS | 2016年 / 124卷 / 06期
关键词：
Prostate cancer; grading; ISUP grade; Gleason grade; PROGNOSTIC-SIGNIFICANCE; GLEASON; CARCINOMA; PROGRESSION; SYSTEM;
D O I：
10.1111/apm.12533
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The International Society of Urological Pathology (ISUP) has issued guidelines for the grading of prostate cancer based on a consensus conference held in 2014. The recommendations resulting from the 2014 consensus conference were a further development of 2005 ISUP modified Gleason grading. In the 2014 system, morphological criteria are clarified, including updated definitions of Gleason pattern 4. In addition to the continued reporting of Gleason scores, we also recommend that Gleason scores 6, 3+4=7, 4+3=7, 8 and 9-10, respectively, be reported as five groups, i.e. ISUP grades 1-5. This new grading system has the dual benefit of predicting patient outcome as well as facilitating patient communication.
引用
收藏
页码：433 / 435
页数：3
相关论文
共 50 条
  • [41] The Value of the 2005 International Society of Urological Pathology (ISUP) Modified Gleason Grading System as Predictor of Biochemical Recurrence Following Radical Prostatectomy
    Billis, A.
    Meirelles, L.
    Freitas, L. L. L. L.
    Costa, L. B. E.
    Bonfitto, J. F. L.
    Diniz, B. L.
    Poletto, P. H.
    Magna, L. A.
    MODERN PATHOLOGY, 2013, 26 : 198A - 198A
  • [42] The value of the 2005 International Society of Urological Pathology (ISUP) modified Gleason grading system as a predictor of biochemical recurrence after radical prostatectomy
    Athanase Billis
    Maisa M.Q. Quintal
    Luciana Meirelles
    Leandro L.L. Freitas
    Larissa B.E. Costa
    João F.L. Bonfitto
    Betina L. Diniz
    Paola H. Poletto
    Luís A. Magna
    Ubirajara Ferreira
    International Urology and Nephrology, 2014, 46 : 935 - 940
  • [43] The value of the 2005 International Society of Urological Pathology (ISUP) modified Gleason grading system as a predictor of biochemical recurrence after radical prostatectomy
    Billis, Athanase
    Quintal, Maisa M. Q.
    Meirelles, Luciana
    Freitas, Leandro L. L.
    Costa, Larissa B. E.
    Bonfitto, Joao F. L.
    Diniz, Betina L.
    Poletto, Paola H.
    Magna, Luis A.
    Ferreira, Ubirajara
    INTERNATIONAL UROLOGY AND NEPHROLOGY, 2014, 46 (05) : 935 - 940
  • [44] SOCS3 immunohistochemical expression to support the 2005 International Society of Urological Pathology (ISUP) modified Gleason grading system.
    Petrone, Gian Luigi
    Pierconti, Francesco
    Martini, Maurizio
    Cenci, Tonia
    Larocca, Luigi Maria
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (02)
  • [45] The Value of the 2005 International Society of Urological Pathology (ISUP) Modified Gleason Grading System as Predictor of Biochemical Recurrence Following Radical Prostatectomy
    Billis, A.
    Meirelles, L.
    Freitas, L. L. L. L.
    Costa, L. B. E.
    Bonfitto, J. F. L.
    Diniz, B. L.
    Poletto, P. H.
    Magna, L. A.
    LABORATORY INVESTIGATION, 2013, 93 : 198A - 198A
  • [46] Prostate cancer. Part 1: Review of cell kinetics over the years 1966-2015 and future perspectives of the new grading of the International Society of Urological Pathology (ISUP)
    Helpap, B.
    Bubendorf, L.
    PATHOLOGE, 2016, 37 (01): : 3 - 10
  • [47] The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia
    Srigley, John R.
    Delahunt, Brett
    Eble, John N.
    Egevad, Lars
    Epstein, Jonathan I.
    Grignon, David
    Hes, Ondrej
    Moch, Holger
    Montironi, Rodolfo
    Tickoo, Satish K.
    Zhou, Ming
    Argani, Pedram
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2013, 37 (10) : 1469 - 1489
  • [48] Molecular pathology of urogenital tumors Recommendations from the 2019 International Society of Urological Pathology (ISUP) Consensus Conference
    Hommerding, Oliver
    Allory, Yves
    Argani, Pedram
    Bismar, Tarek A.
    Bubendorf, Lukas
    Canete-Portillo, Sofia
    Chaux, Alcides
    Chen, Ying-Bei
    Cheng, Liang
    Cubilla, Antonio L.
    Egevad, Lars
    Gill, Anthony J.
    Grignon, David J.
    Hartmann, Arndt
    Hes, Ondrej
    Idrees, Muhammad T.
    Kao, Chia-Sui
    Knowles, Margaret A.
    Looijenge, Leendert H. J.
    Lota, Tamara L. N.
    Pritchard, Colin C.
    Rubin, Mark A.
    Fins, Scott A. Tom
    Van der Kwast, Theodorus H.
    Velazquez, Elsa F.
    Warrick, Joshua, I
    Williamson, Sean R.
    Kristiansen, Glen
    PATHOLOGE, 2021, 42 (03): : 310 - 318
  • [49] Handling and Staging of Renal Cell Carcinoma The International Society of Urological Pathology Consensus (ISUP) Conference Recommendations
    Trpkov, Kiril
    Grignon, David J.
    Bonsib, Stephen M.
    Amin, Mahul B.
    Billis, Athanase
    Lopez-Beltran, Antonio
    Samaratunga, Hemamali
    Tamboli, Pheroze
    Delahunt, Brett
    Egevad, Lars
    Montironi, Rodolfo
    Srigley, John R.
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2013, 37 (10) : 1505 - 1517
  • [50] Performance of a validated urine exosome gene expression assay to predict high-grade prostate cancer utilizing the International Society of Urological Pathology (ISUP) 2014 grading system.
    Donovan, Michael
    Torkler, Phillipp
    Skog, Johan
    Noerholm, Mikkel
    Carroll, Peter
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (06)
12345