Major metabolites of ginseng sapogenins formed by rat liver microsomes

被引：0
|
作者：
Kasai, R [1 ]
Hara, K [1 ]
Dokan, R [1 ]
Suzuki, N [1 ]
Mizutare, T [1 ]
Yoshihara, S [1 ]
Yamasaki, K [1 ]
机构：
[1] Hiroshima Univ, Fac Med, Inst Pharmaceut Sci, Minami Ku, Hiroshima 7348551, Japan
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 2000年 / 48卷 / 08期
关键词：
microsomal metabolite; ginsenoside; 20(S)-protopanaxatriol; 20(S)-protopanaxatriol oxide; 20(S)-protopanaxadiol; 20(S)-protopanaxadiol oxide;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Incubation of ginseng sapogenins with microsomes from rat liver resulted in formation of their 20,24-epoxides as major metabolites. Identification of the metabolites was performed by HPLC, FAB-MS and EI-MS.
引用
收藏
页码：1226 / 1227
页数：2
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