Dengue fever in patients under biologics

被引：11

作者：

Deligny, Christophe ^{[1
]}

de Bandt, Michel ^{[1
]}

Dehlinger, Veronique ^{[1
]}

Numeric, Patrick ^{[2
]}

Cabie, Andre ^{[3
]}

Lombard, Frederic ^{[4
]}

Polomat, Katlyne ^{[1
]}

JeanBaptiste, Georges ^{[1
]}

Arfi, Serge ^{[1
]}

机构：

[1] Univ Hosp Pierre Zobda Quitman, Serv Med Interne & Rhumatol 3C 5D, F-97261 Fort De France, Martinique, France

[2] Univ Hosp Pierre Zobda Quitman, Internal Med Unit 3D, F-97261 Fort De France, Martinique, France

[3] Univ Hosp Pierre Zobda Quitman, Serv Malad Infect, F-97261 Fort De France, Martinique, France

[4] Univ Hosp Pierre Zobda Quitman, Serv Hepatogastroenterol, F-97261 Fort De France, Martinique, France

来源：

JOURNAL OF CLINICAL VIROLOGY | 2014年 / 61卷 / 03期

关键词：

Biotherapy; Dengue fever; Rheumatoid arthritis; anti-TNF; Rituximab; NECROSIS-FACTOR-ALPHA; SEVERITY;

D O I：

10.1016/j.jcv.2014.08.011

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Dengue fever (DF) is an epidemic viral mosquito-borne infection limited to tropical and subtropical countries. Biological therapies have been frequently used for the last 15 years in the treatment of inflammatory rheumatic conditions like rheumatoid arthritis. However, no data is available regarding the characteristics of this infection in patients on biological therapy. Yet, numerous patients on biotherapy have holidays in countries where DF exists. Moreover, the mosquitoes Aedes albopictus, vector of this viral disease, is now found in some developed countries such as southern Europe and the USA, allowing the possibility of a DF outbreak. We conducted a survey of individuals on biotherapy and described a case series of the patients experiencing DF. Our 8 patients on biotherapy (anti-TNF, n = 6; rituximab, n = 2) for a rheumatic condition did not experience severe DF. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：442 / 443

页数：2

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