Production technologies for monoclonal antibodies and their fragments

被引：106
|
作者：
Andersen, DC [1 ]
Reilly, DE [1 ]
机构：
[1] Genentech Inc, San Francisco, CA 94080 USA
来源：
CURRENT OPINION IN BIOTECHNOLOGY | 2004年 / 15卷 / 05期
关键词：
D O I：
10.1016/j.copbio.2004.08.002
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
In recent years, monoclonal antibodies have emerged as an increasingly important class of human therapeutics. A variety of forms of antibodies, including fragments such as Fabs, Fab'(2)s and single-chain Fvs, are also being evaluated for a range of different purposes. A variety of expression systems and improvements within these systems have been developed to address these growing and diverse needs.
引用
收藏
页码：456 / 462
页数：7
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