The Roles of CD147 and/or Cyclophilin A in Kidney Diseases

被引：32
|
作者：
Qu, Xin [1 ,2 ]
Wang, Chunting [1 ]
Zhang, Jicheng [1 ]
Qie, Guoqiang [1 ]
Zhou, Jianxin [2 ]
机构：
[1] Shandong Univ, Shandong Prov Hosp, Dept Crit Care Med, Jinan 250021, Peoples R China
[2] Capital Med Univ, Beijing Tiantan Hosp, Dept Crit Care Med, Beijing 100050, Peoples R China
来源：
MEDIATORS OF INFLAMMATION | 2014年 / 2014卷
基金：
中国国家自然科学基金; 中国博士后科学基金;
关键词：
MATRIX METALLOPROTEINASE INDUCER; IMMUNOGLOBULIN SUPERFAMILY; THERAPEUTIC TARGET; CELL-PROLIFERATION; GLYCOPROTEIN CE9; MOUSE BASIGIN; RAT OX-47; EMMPRIN; EXPRESSION; INFLAMMATION;
D O I：
10.1155/2014/728673
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
CD147 is a widely expressed integral plasma membrane glycoprotein and has been involved in a variety of physiological and pathological activities in combination with different partners, including cyclophilins, caveolin-1, monocarboxylate transporters, and integrins. Recent data demonstrate that both CyPA and CD147 significantly contribute to renal inflammation, acute kidney injury, renal fibrosis, and renal cell carcinoma. Here we review the current understanding of cyclophilin A and CD147 expression and functions in kidney diseases and potential implications for treatment of kidney diseases.
引用
收藏
页数：10
相关论文
共 50 条
  • [21] Cyclophilin A/CD147 interactions participate in early brain injury after subarachnoid hemorrhage in rats
    Dang, B.
    Wang, Z.
    Chen, G.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2017, 37 : 114 - 115
  • [22] Solution Characterization of the Extracellular Region of CD147 and Its Interaction with Its Enzyme Ligand Cyclophilin A
    Schlegel, Jennifer
    Redzic, Jasmina S.
    Porter, Christopher C.
    Yurchenko, Vyacheslav
    Bukrinsky, Michael
    Labeikovsky, Wladimir
    Armstrong, Geoffrey S.
    Zhang, Fengli
    Isern, Nancy G.
    DeGregori, James
    Hodges, Robert
    Elsenmesser, Elan Zohar
    JOURNAL OF MOLECULAR BIOLOGY, 2009, 391 (03) : 518 - 535
  • [23] Author Correction: The Cyclophilin A–CD147 complex promotes the proliferation and homing of multiple myeloma cells
    Di Zhu
    Zhongqiu Wang
    Jian-Jun Zhao
    Teresa Calimeri
    Jiang Meng
    Teru Hideshima
    Mariateresa Fulciniti
    Yue Kang
    Scott B. Ficarro
    Yu-Tzu Tai
    Zachary Hunter
    Douglas McMilin
    Haoxuan Tong
    Constantine S. Mitsiades
    Catherine J. Wu
    Steven P. Treon
    David M. Dorfman
    Geraldine Pinkus
    Nikhil C. Munshi
    Pierfrancesco Tassone
    Jarrod A. Marto
    Kenneth C. Anderson
    Ruben D. Carrasco
    Nature Medicine, 2024, 30 : 1210 - 1210
  • [24] CYCLOPHILIN A/CD147 INTERACTIONS PARTICIPATE IN EARLY BRAIN INJURY AFTER SUBARACHNOID HEMORRHAGE IN RATS
    Dang, B.
    Li, H.
    Meng, C.
    Shen, H.
    Wang, Y.
    Gao, A.
    Duan, X.
    Wang, Z.
    Chen, G.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2016, 36 : 345 - 347
  • [25] CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A
    Pushkarsky, T
    Zybarth, G
    Dubrovsky, L
    Yurchenko, V
    Tang, H
    Guo, HM
    Toole, B
    Sherry, B
    Bukrinsky, M
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (11) : 6360 - 6365
  • [26] Cyclophilin A is overexpressed in human pancreatic cancer cells and stimulates cell proliferation through CD147
    Li, M
    Zhai, QH
    Bharadwaj, U
    Wang, H
    Li, F
    Fisher, WE
    Chen, CY
    Yao, QZ
    CANCER, 2006, 106 (10) : 2284 - 2294
  • [27] CD147与生殖
    邵长好
    马秀菊
    中国妇幼健康研究, 2007, (06) : 533 - 535
  • [28] CD147 stimulates hepatoma cells escaping from immune surveillance of T cells by interaction with Cyclophilin A
    Ren, Yi-xin
    Wang, Shu-jing
    Fan, Jian-hui
    Sun, Shi-jie
    Li, Xia
    Padhiar, Arshad Ahmed
    Zhang, Jia-ning
    BIOMEDICINE & PHARMACOTHERAPY, 2016, 80 : 289 - 297
  • [29] The binding of extracellular cyclophilin A to ACE2 and CD147 triggers psoriasis-like inflammation
    Yang, Wenxian
    Bai, Xiaoyuan
    Jia, Xiaoxiao
    Li, Huizi
    Min, Jie
    Li, Heqiao
    Zhang, Haoran
    Zhou, Jianjing
    Zhao, Yuna
    Liu, Wenjun
    Xin, Haiming
    Sun, Lei
    JOURNAL OF AUTOIMMUNITY, 2024, 148
  • [30] Regulation of CD147 cell surface expression - Involvement of the proline residue in the CD147 transmembrane domain
    Yurchenko, V
    Pushkarsky, T
    Li, JH
    Dai, WW
    Sherry, B
    Bukrinsky, M
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (17) : 17013 - 17019
12345