Calmodulin and excitation-contraction coupling

被引:0
|
作者
Hamilton, SL
Serysheva, I
Strasburg, GM
机构
[1] Baylor Coll Med, Dept Physiol & Mol Biophys, Houston, TX 77030 USA
[2] Michigan State Univ, Dept Food Sci & Human Nutr, E Lansing, MI 48824 USA
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中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Excitation-contraction coupling in cardiac and skeletal muscle involves the transverse-tubule voltage-dependent Ca2+ channel and the sarcoplasmic reticulum Ca2+ release channel Both of these ion channels bind and are modulated by calmodulin in both ifs Ca2+-bound and Ca2+-free forms. Calmodulin is, therefore, potentially an important regulator of excitation-contraction coupling. Ifs precise role, however, has not yet been defined.
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页码:281 / 284
页数:4
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