Role of in vitro metabolic interactions in the conduct of drug-drug interaction (DDI) studies.

被引:0
|
作者
Yuan, R [1 ]
Balian, JD [1 ]
Svadjian, R [1 ]
Uppoor, RS [1 ]
Ajayi, F [1 ]
Burnett, A [1 ]
Lesko, LJ [1 ]
Marroum, P [1 ]
机构
[1] US FDA, Ctr Drug Evaluat & Res, Off Clin Pharmacol & Biopharm, Rockville, MD 20857 USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
PIII46
引用
收藏
页码:218 / 218
页数:1
相关论文
共 50 条
  • [41] The effects of dose staggering on metabolic drug-drug interactions
    Yang, JS
    Kjellsson, M
    Rostami-Hodjegan, A
    Tucker, GT
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2003, 20 (02) : 223 - 232
  • [42] Volume of Distribution is Unaffected by Metabolic Drug-Drug Interactions
    Sodhi, Jasleen K.
    Huang, Caroline H.
    Benet, Leslie Z.
    CLINICAL PHARMACOKINETICS, 2021, 60 (02) : 205 - 222
  • [43] The impact of in vitro binding on in vitro -: In vivo extrapolations, projections of metabolic clearance and clinical drug-drug interactions
    Grime, K
    Riley, RJ
    CURRENT DRUG METABOLISM, 2006, 7 (03) : 251 - 264
  • [44] DDI-MuG: Multi-aspect graphs for drug-drug interaction extraction
    Yang, Jie
    Ding, Yihao
    Long, Siqu
    Poon, Josiah
    Han, Soyeon Caren
    FRONTIERS IN DIGITAL HEALTH, 2023, 5
  • [45] PHARMACOKINETIC (PK) BASIS OF STATIN DRUG-DRUG INTERACTION (DDI) INFORMATION IN FDA LABELS
    Mease, J.
    Ramamoorthy, A.
    Yang, X.
    Madabushi, R.
    Fletcher, E. Pfuma
    Zineh, I.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2023, 113 : S13 - S13
  • [46] DDI-SSL: Drug-Drug Interaction Prediction Based on Substructure Signature Learning
    Liang, Yuan
    APPLIED SCIENCES-BASEL, 2023, 13 (19):
  • [47] DRUG-DRUG INTERACTION DATABASES: SENSITIVITY AND SPECIFICITY TO DETECT MANIFEST DRUG-DRUG INTERACTIONS, RELIABILITY RATINGS AND MANAGEMENT STRATEGIES OF POTENTIAL DRUG-DRUG INTERACTIONS
    Ocovska, Z.
    Marikova, M.
    Kukralova, K.
    Vlcek, J.
    VALUE IN HEALTH, 2022, 25 (01) : S140 - S141
  • [48] Role of inhibitory metabolites in drug-drug interactions
    Isoherranen, Nina
    DRUG METABOLISM REVIEWS, 2006, 38 : 6 - 7
  • [49] Drug-Drug Interaction (DDI) between Felodipine and Irinotecan During the Treatment of Ovarian Cancer
    Chen, Fang
    Zhou, Ping
    LATIN AMERICAN JOURNAL OF PHARMACY, 2018, 37 (03): : 449 - 451
  • [50] Predictive power of an in vitro system to assess drug interactions of an antimuscarinic medication: A comparison of in vitro and in vivo drug-drug interaction studies of trospium chloride with digoxin
    Sandage, B.
    Sabounjian, L.
    Shipley, J.
    Profy, A.
    Lasseter, K.
    Fox, L.
    Harnett, M.
    JOURNAL OF CLINICAL PHARMACOLOGY, 2006, 46 (07): : 776 - 784