Treatment of Alopecia Areata With Topical Sensitizers

被引：13

作者：

Sutherland, Lesley ^{[1
]}

Laschinger, Mary ^{[1
]}

Syed, Zain U. ^{[1
]}

Gaspari, Anthony ^{[1
]}

机构：

[1] Univ Maryland, Sch Med, Dept Dermatol, Baltimore, MD 21201 USA

来源：

DERMATITIS | 2015年 / 26卷 / 01期

关键词：

HUMAN HAIR FOLLICLE; SQUARIC ACID; IMMUNE PRIVILEGE; SUBSTANCE-P; IMMUNOTHERAPY; DIPHENCYPRONE; DIPHENYLCYCLOPROPENONE; TOTALIS; GROWTH; CONTAMINANTS;

D O I：

10.1097/DER.0000000000000094

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

For those with severe alopecia areata, with greater than 50% scalp involvement, topical immunotherapy with diphenylcyclopropenone or squaric acid dibutylester is considered the treatment of choice. This article not only reviews the safety and efficacy of topical sensitizers for the treatment of alopecia areata but also highlights strides that have been made in the literature concerning their use in pediatric populations, molecular mechanisms of efficacy, and improved safety through targeted delivery methods.

引用

页码：26 / 31

页数：6

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