Stereoselective aldol reactions using pseudo C2 symmetric 1-benzyl-4-(trifluoromethyl)-piperidine-2,6-dione

被引：3

作者：

Inoue, Yuta ^{[1
]}

Hatayama, Takahiro ^{[1
]}

Kawasaki-Takasuka, Tomoko ^{[1
]}

Agou, Tomohiro ^{[2
]}

Kubota, Toshio ^{[2
]}

Yamazaki, Takashi ^{[1
]}

机构：

[1] Tokyo Univ Agr & Technol, Div Appl Chem, Inst Engn, 2-24-16 Nakamachi, Koganei, Tokyo 1848588, Japan

[2] Ibaraki Univ, Dept Biomol Funct Engn, Nakanarusawa 4-12-1, Hitachi, Ibaraki 3168511, Japan

来源：

CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 71期

关键词：

CHIRAL ALDEHYDES; DESYMMETRIZATION; DERIVATIVES; KETONES;

D O I：

10.1039/c8cc05458d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Crossed aldol reactions of the CF3-containing pseudo C-2 symmetric cyclic imide 3 were carried out by way of the corresponding boron bisenolate to stereoselectively furnish the desired products 4 and this procedure allowed the preferential construction of the diastereomers of the compounds previously obtained from the acyclic counterpart 1.

引用

页码：9913 / 9916

页数：4