Stereoselective aldol reactions using pseudo C2 symmetric 1-benzyl-4-(trifluoromethyl)-piperidine-2,6-dione

被引：3
|
作者：
Inoue, Yuta [1 ]
Hatayama, Takahiro [1 ]
Kawasaki-Takasuka, Tomoko [1 ]
Agou, Tomohiro [2 ]
Kubota, Toshio [2 ]
Yamazaki, Takashi [1 ]
机构：
[1] Tokyo Univ Agr & Technol, Div Appl Chem, Inst Engn, 2-24-16 Nakamachi, Koganei, Tokyo 1848588, Japan
[2] Ibaraki Univ, Dept Biomol Funct Engn, Nakanarusawa 4-12-1, Hitachi, Ibaraki 3168511, Japan
来源：
CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 71期
关键词：
CHIRAL ALDEHYDES; DESYMMETRIZATION; DERIVATIVES; KETONES;
D O I：
10.1039/c8cc05458d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Crossed aldol reactions of the CF3-containing pseudo C-2 symmetric cyclic imide 3 were carried out by way of the corresponding boron bisenolate to stereoselectively furnish the desired products 4 and this procedure allowed the preferential construction of the diastereomers of the compounds previously obtained from the acyclic counterpart 1.
引用
收藏
页码：9913 / 9916
页数：4
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