Candida auris: a worrisome, globally emerging pathogen
被引:55
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作者:
Navalkele, Bhagyashri D.
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机构:
Wayne State Univ, Detroit Med Ctr, Div Infect Dis, Detroit, MI USAWayne State Univ, Detroit Med Ctr, Div Infect Dis, Detroit, MI USA
Navalkele, Bhagyashri D.
[1
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Revankar, Sanjay
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Wayne State Univ, Infect Dis Fellowship Program, Internal Med & Infect Dis, Detroit, MI USAWayne State Univ, Detroit Med Ctr, Div Infect Dis, Detroit, MI USA
Revankar, Sanjay
[2
]
Chandrasekar, Pranatharthi
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Wayne State Univ, Karmanos Canc Inst, Internal Med & Infect Dis, Div Infect Dis, Detroit, MI USAWayne State Univ, Detroit Med Ctr, Div Infect Dis, Detroit, MI USA
Chandrasekar, Pranatharthi
[3
]
机构:
[1] Wayne State Univ, Detroit Med Ctr, Div Infect Dis, Detroit, MI USA
[2] Wayne State Univ, Infect Dis Fellowship Program, Internal Med & Infect Dis, Detroit, MI USA
[3] Wayne State Univ, Karmanos Canc Inst, Internal Med & Infect Dis, Div Infect Dis, Detroit, MI USA
Introduction: Candida auris is a recently discovered, rapidly emerging fungal pathogen. Infections due to C. auris are hospital-acquired, multidrug resistant and associated with high mortality.Areas covered: This review highlights epidemiology, pathogenesis, microbiological characteristics, clinical presentation, diagnostic challenges and treatment options of C. auris infections. Infection prevention measures to prevent spread of C. auris and special measures during an outbreak situation have also been reviewed.Expert commentary: Rapid emergence of hospital onset C. auris is worrisome. Early diagnosis of C. auris is essential for better outcomes and the implementation of infection prevention measures. Lack of widespread awareness, absence of general availability of diagnostic testing methods, and limited options for treatment of C. auris infections make it a difficult-to-treat pathogen. Further studies are needed for better understanding of this emerging pathogen.
机构:
Farwania Hosp, Dept Labs, Microbiol Unit, Sabah Al Nasser, Kuwait
Kuwait Univ, Dept Microbiol, Fac Med, Kuwait, KuwaitFarwania Hosp, Dept Labs, Microbiol Unit, Sabah Al Nasser, Kuwait
Alfouzan, Wadha
Dhar, Rita
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Farwania Hosp, Dept Labs, Microbiol Unit, Sabah Al Nasser, KuwaitFarwania Hosp, Dept Labs, Microbiol Unit, Sabah Al Nasser, Kuwait
Dhar, Rita
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Albarrag, Ahmed
Al-Abdely, Hail
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机构:
King Faisal Specialist Hosp & Res Ctr, Infect Dis Sect, Dept Med, Riyadh, Saudi ArabiaFarwania Hosp, Dept Labs, Microbiol Unit, Sabah Al Nasser, Kuwait
机构:
Yonsei Univ, Coll Life Sci & Biotechnol, Dept Biotechnol, Seoul 03722, South KoreaYonsei Univ, Coll Life Sci & Biotechnol, Dept Biotechnol, Seoul 03722, South Korea
Cha, Hyunjin
Bahn, Yong-Sun
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Yonsei Univ, Coll Life Sci & Biotechnol, Dept Biotechnol, Seoul 03722, South KoreaYonsei Univ, Coll Life Sci & Biotechnol, Dept Biotechnol, Seoul 03722, South Korea