Candida auris: a worrisome, globally emerging pathogen
被引:55
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作者:
Navalkele, Bhagyashri D.
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机构:
Wayne State Univ, Detroit Med Ctr, Div Infect Dis, Detroit, MI USAWayne State Univ, Detroit Med Ctr, Div Infect Dis, Detroit, MI USA
Navalkele, Bhagyashri D.
[1
]
Revankar, Sanjay
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机构:
Wayne State Univ, Infect Dis Fellowship Program, Internal Med & Infect Dis, Detroit, MI USAWayne State Univ, Detroit Med Ctr, Div Infect Dis, Detroit, MI USA
Revankar, Sanjay
[2
]
Chandrasekar, Pranatharthi
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机构:
Wayne State Univ, Karmanos Canc Inst, Internal Med & Infect Dis, Div Infect Dis, Detroit, MI USAWayne State Univ, Detroit Med Ctr, Div Infect Dis, Detroit, MI USA
Chandrasekar, Pranatharthi
[3
]
机构:
[1] Wayne State Univ, Detroit Med Ctr, Div Infect Dis, Detroit, MI USA
[2] Wayne State Univ, Infect Dis Fellowship Program, Internal Med & Infect Dis, Detroit, MI USA
[3] Wayne State Univ, Karmanos Canc Inst, Internal Med & Infect Dis, Div Infect Dis, Detroit, MI USA
Introduction: Candida auris is a recently discovered, rapidly emerging fungal pathogen. Infections due to C. auris are hospital-acquired, multidrug resistant and associated with high mortality.Areas covered: This review highlights epidemiology, pathogenesis, microbiological characteristics, clinical presentation, diagnostic challenges and treatment options of C. auris infections. Infection prevention measures to prevent spread of C. auris and special measures during an outbreak situation have also been reviewed.Expert commentary: Rapid emergence of hospital onset C. auris is worrisome. Early diagnosis of C. auris is essential for better outcomes and the implementation of infection prevention measures. Lack of widespread awareness, absence of general availability of diagnostic testing methods, and limited options for treatment of C. auris infections make it a difficult-to-treat pathogen. Further studies are needed for better understanding of this emerging pathogen.
机构:
Univ Wisconsin, Dept Med, Madison, WI 53706 USA
Univ Wisconsin, Dept Med Microbiol, Madison, WI 53706 USA
Univ Wisconsin, Dept Immunol, Madison, WI 53706 USAUniv Wisconsin, Dept Med, Madison, WI 53706 USA
机构:
Univ Utah, Dept Med, Div Infect Dis, Salt Lake City, UT 84112 USAUniv Utah, Dept Med, Div Infect Dis, Salt Lake City, UT 84112 USA
Spivak, Emily S.
Hanson, Kimberly E.
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机构:
Univ Utah, Dept Med, Div Infect Dis, Salt Lake City, UT 84112 USA
Univ Utah, Dept Pathol, Clin Microbiol Div, Salt Lake City, UT 84112 USAUniv Utah, Dept Med, Div Infect Dis, Salt Lake City, UT 84112 USA