Human myeloma cells express the bone regulating gene Runx2/Cbfa1 and produce osteopontin that it is involved in myeloma-induced angiogenesis.

被引:0
|
作者
Giuliani, N [1 ]
Colla, S [1 ]
Morandi, F [1 ]
Bonomini, S [1 ]
Crugnola, M [1 ]
Rizzoli, V [1 ]
机构
[1] Univ Parma, I-43100 Parma, Italy
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
2344
引用
收藏
页码:645A / 645A
页数:1
相关论文
共 47 条
  • [31] Myeloma cells block Runx2/CbfaI activity in human bone marrow osteoblast progenitors and inhibit osteoblast formation and differentiation.
    Giuliani, N
    Colla, S
    Morandi, F
    Bonomini, S
    Rizzoli, V
    BLOOD, 2004, 104 (11) : 183A - 183A
  • [32] Dominant role of CD47-thrombospondin-1 interactions in myeloma-induced fusion of human dendritic cells: implications for bone disease
    Kukreja, Anjli
    Radfar, Soroosh
    Sun, Ben-Hua
    Insogna, Karl
    Dhodapkar, Madhav V.
    BLOOD, 2009, 114 (16) : 3413 - 3421
  • [33] Smad3 interacts with JunB and Cbfa1/Runx2 for transforming growth factor-β-stimulated collagenase-3 expression in human breast cancer cells
    Selvamurugan, N
    Kwok, S
    Partridge, NC
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (26) : 27764 - 27773
  • [34] Gfi1 Inhibits Osteoblast Differentiation in Multiple Myeloma by Inducing Epigenetic Repression of Runx2 in Bone Marrow Stromal Cells.
    Adamik, Juraj
    Sun, Quanhong
    Roodman, G. David
    Galson, Deborah
    JOURNAL OF BONE AND MINERAL RESEARCH, 2014, 29 : S54 - S54
  • [35] Antisense targeting of TGF-β1 augments BMP-induced upregulation of osteopontin, type I collagen and Cbfa1 in human Saos-2 cells
    Shen, Zhong-Jian
    Kim, Sang Kook
    Jun, Do Youn
    Park, Wan
    Kim, Young Ho
    Malter, James S.
    Moon, Byung Jo
    EXPERIMENTAL CELL RESEARCH, 2007, 313 (07) : 1415 - 1425
  • [36] The Transcription Repressor Gfi1 Directly Interacts With and Is Phosphorylated By Aurora A Kinase, Which Abrogates Myeloma-Induced Gfi1 Repression Of The Runx2 Promoter In Pre-Osteoblasts
    Ding, Jixin
    Wang, Fengming
    Jin, ShunQian
    Anderson, Judy
    Galson, Deborah L.
    Roodman, G. David
    BLOOD, 2013, 122 (21)
  • [37] Smad3 interacts with JunB and Cbfa1/Runx2 for transforming growth factor-betal-stimulated collagenase-3 expression in human breast cancer cells.
    Selvamurugan, N
    Kwok, S
    Partridge, NC
    JOURNAL OF BONE AND MINERAL RESEARCH, 2003, 18 : S198 - S198
  • [38] Smad3 interacts with JunB and Cbfa1/Runx2 for transforming growth factor-betal-stimulated collagenase-3 expression in human breast cancer cells.
    Selvamurugan, N
    Kwok, S
    Partridge, NC
    JOURNAL OF BONE AND MINERAL RESEARCH, 2004, 19 : S227 - S227
  • [39] Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity
    Sierra, J
    Villagra, A
    Paredes, R
    Cruzat, F
    Gutierrez, S
    Javed, A
    Arriagada, G
    Olate, J
    Imschenetzky, M
    van Wijnen, AJ
    Lian, JB
    Stein, GS
    Stein, JL
    Montecino, M
    MOLECULAR AND CELLULAR BIOLOGY, 2003, 23 (09) : 3339 - 3351
  • [40] XRK3F2 Inhibition of p62-ZZ Domain Signaling Rescues Myeloma-Induced GFI1-Driven Epigenetic Repression of the Runx2 Gene in Pre-osteoblasts to Overcome Differentiation Suppression
    Adamik, Juraj
    Silbermann, Rebecca
    Marino, Silvia
    Sun, Quanhong
    Anderson, Judith L.
    Zhou, Dan
    Xie, Xiang-Qun
    Roodman, G. David
    Galson, Deborah L.
    FRONTIERS IN ENDOCRINOLOGY, 2018, 9