Synthesis and Antimicrobial Activity of 7-Amino cephalosporanic Acid Derivatives of Amino Acids and Peptides

被引:0
|
作者
Himaja, M. [1 ]
Desai, Siddharth [1 ]
Sambanthan, A. Thirugnana [1 ]
Ranjitha, J. [1 ]
机构
[1] VIT Univ, Sch Adv Sci, Div Chem, Vellore 632014, Tamil Nadu, India
关键词
7-Aminocephalosporanic acid; Amino acids; Dipeptides; Antibacterial and Antifungal activities;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel series of 7-amino cephalosporanic acid derivatives of amino acid and peptides were synthesized by solution phase technique. The synthesized compounds were tested for their biological activities against bacterial and fungal organisms. All the compounds showed potent antifungal activity and most of the compounds have shown moderate antibacterial activities. The structures of the newly synthesized compounds were confirmed by IR, (1)H NMR and mass spectral analysis.
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页码:2914 / 2918
页数:5
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