Occurrence of Allergens in Cosmetics for Sensitive Skin

被引:9
|
作者
Martins, Marcia S. [1 ,2 ]
Ferreira, Marta S. [3 ,4 ]
Almeida, Isabel F. [3 ,4 ]
Sousa, Emilia [1 ,2 ]
机构
[1] Univ Porto, Fac Pharm, Dept Chem Sci, Lab Organ & Pharmaceut Chem, P-4050313 Porto, Portugal
[2] CIIMAR Interdisciplinary Ctr Marine & Environm Re, Ave Gen Norton Matos S-N, P-4450208 Matosinhos, Portugal
[3] Univ Porto, Lab Pharmaceut Technol, Dept Drug Sci, UCIBIO Appl Mol Biosci Unit,MedTech,Fac Pharm, P-4050313 Porto, Portugal
[4] Univ Porto, Fac Pharm, Associate Lab I4HB, Inst Hlth & Bioecon, P-4050313 Porto, Portugal
关键词
sensitive skin; allergens; cosmetic products; fragrance; sensitization; CONTACT-DERMATITIS; SAFETY ASSESSMENT; CETYL ALCOHOL; EMERGING ALLERGEN; ALKYL GLUCOSIDES; STRATUM-CORNEUM; FINAL REPORT; CHLORPHENESIN; ETHYLHEXYLGLYCERIN; PHOSPHATE;
D O I
10.3390/cosmetics9020032
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Sensitive skin is characterized by symptoms such as stinging and tingling in response to stimuli that usually do not cause unpleasant sensations. Epidemiological studies show that individuals with sensitive skin are more prone to developing skin allergies, although the link between both conditions is unknown. Aiming to evaluate the presence of allergens in facial-skin products for sensitive skin, a pool of 88 cosmetic products from international brands marketed in pharmacies and parapharmacies was analyzed. A list of allergens identified in product labels was compiled and grouped according to their function. Fragrances were the most common allergens, followed by skin-conditioning agents, surfactants, and preservatives. Fragrances presenting the highest use percentages were linalool, benzyl alcohol, geraniol, and citronellol. Overall, the majority of cosmetic formulations were absent of fragrance allergens, being present only in 7% of products. Other allergens were found in most products (95%). This finding should be interpreted with caution, since many of these compounds are rare sensitizers and studies demonstrating their risk for individuals with sensitive skin are lacking. With this study, useful information for health professionals is provided to support their advice and to help consumers choosing cosmetic products.
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页数:13
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