Molecular docking of ursolic acid and Staphylococcus aureus ATPase for antibacterial therapy

被引:0
|
作者
Maggi, Norbert [1 ]
Schito, Anna Maria [2 ]
Iobbi, Valeria [3 ]
Bisio, Angela [3 ]
Ruggiero, Carmelina [1 ]
Giacomini, Mauro [1 ]
机构
[1] Univ Genoa, Dept Informat Bioengn Robot & Syst Engn, Genoa, Italy
[2] Univ Genoa, Dept Integrated Surg & Diagnost Sci, Genoa, Italy
[3] Univ Genoa, Dept Pharm, Genoa, Italy
关键词
Antibacterial resistance; molecular docking; ursolic acid; Staphylococcus aureus; ANTIMICROBIAL ACTIVITY; AUTOMATED DOCKING; SALVIA-CORRUGATA; DITERPENOIDS; RELEVANCE;
D O I
10.1109/melecon48756.2020.9140570
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Antibiotics have transformed the practice of medicine, making once lethal infections easily treatable and making other medical advances possible. The abuse of antibiotics has contributed to the growing problem of antibiotic resistance, which has become one of the most serious and growing threats to public health. Ursolic acid is one of the most promising substances of biological origin for antimicrobial therapy. A molecular docking with Staphylococcus aureus ATPase is presented.
引用
收藏
页码:372 / 375
页数:4
相关论文
共 50 条
  • [41] Evaluation of fusidic acid in therapy of experimental Staphylococcus aureus meningitis
    Ostergaard, C
    Yieng-Kow, RV
    Knudsen, JD
    Frimodt-Moller, N
    Espersen, F
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2003, 51 (05) : 1301 - 1305
  • [42] The use of chlorogenic acid and its analogues as inhibitors: an investigation of the inhibition of sortase A of Staphylococcus aureus using molecular docking and dynamic simulation
    Bi, Chongwei
    Wang, Lin
    Niu, Xiaodi
    Cai, Hongjun
    Zhong, Xiaobo
    Deng, Xuming
    Wang, Tiedong
    Wang, Dacheng
    BIOTECHNOLOGY LETTERS, 2016, 38 (08) : 1341 - 1347
  • [43] The use of chlorogenic acid and its analogues as inhibitors: an investigation of the inhibition of sortase A of Staphylococcus aureus using molecular docking and dynamic simulation
    Chongwei Bi
    Lin Wang
    Xiaodi Niu
    Hongjun Cai
    Xiaobo Zhong
    Xuming Deng
    Tiedong Wang
    Dacheng Wang
    Biotechnology Letters, 2016, 38 : 1341 - 1347
  • [44] Using network pharmacology and molecular docking verification to explore the mechanism of ursolic acid in the treatment of osteoporosis
    Yang, Bowen
    Zhu, Qiuwen
    Wang, Xiaodong
    Mao, Jingxin
    Zhou, Shuqing
    MEDICINE, 2022, 101 (49) : E32222
  • [45] The potential mechanism of ursolic acid in the treatment of bladder cancer based on network pharmacology and molecular docking
    Huang, Xiao-Long
    Sun, Yan
    Wen, Peng
    Pan, Jun-Cheng
    He, Wei-Yang
    JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2024, 52 (03)
  • [46] Antibacterial effect of silver nanoparticles on Staphylococcus aureus
    Mirzajani, Fateme
    Ghassempour, Alireza
    Aliahmadi, Atousa
    Esmaeili, Mohammad Ali
    RESEARCH IN MICROBIOLOGY, 2011, 162 (05) : 542 - 549
  • [47] Antibacterial effect of silver nanoparticles on Staphylococcus aureus
    Wen-Ru Li
    Xiao-Bao Xie
    Qing-Shan Shi
    Shun-Shan Duan
    You-Sheng Ouyang
    Yi-Ben Chen
    BioMetals, 2011, 24 : 135 - 141
  • [48] Antibacterial mechanism of soybean isoflavone on Staphylococcus aureus
    Qian Wang
    Haitao Wang
    Mingjie Xie
    Archives of Microbiology, 2010, 192 : 893 - 898
  • [49] Antibacterial activity of propolis against Staphylococcus aureus
    Lu, LC
    Chen, YW
    Chou, CC
    INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2005, 102 (02) : 213 - 220
  • [50] Antibacterial effect of silver nanoparticles on Staphylococcus aureus
    Li, Wen-Ru
    Xie, Xiao-Bao
    Shi, Qing-Shan
    Duan, Shun-Shan
    Ouyang, You-Sheng
    Chen, Yi-Ben
    BIOMETALS, 2011, 24 (01) : 135 - 141