A Concise, Metal-Free Approach to the Synthesis of Oxime Ethers from Cross-Dehydrogenative-Coupling of sp3 C-H Bonds with Oximes

被引：51
|
作者：
Jin, Jun [1 ]
Li, Yan [1 ]
Wang, Zhi-jing [1 ]
Qian, Wei-xing [1 ]
Bao, Wei-liang [1 ]
机构：
[1] Zhejiang Univ, Dept Chem, Hangzhou 310028, Peoples R China
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 2010卷 / 07期
基金：
高等学校博士学科点专项科研基金;
关键词：
Oxime ethers; C-H activation; Allylic compounds; Cross-coupling; Dehydrogenation; IODIDE-MEDIATED ALLYLATION; CARBON RADICAL-ADDITION; ALPHA-AMINO-ACIDS; ASYMMETRIC-SYNTHESIS; ORGANOLITHIUM REAGENTS; ALLYLIC SUBSTITUTION; CYCLIZATION REACTION; GENERAL-SYNTHESIS; HIGHLY EFFICIENT; C=N BOND;
D O I：
10.1002/ejoc.200901321
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A concise oxime ether synthesis by a metal-free dehydrogenative cross-coupling reaction between allylic sp(3) C-H bonds and oximes promoted by 2,3-dichloro-5,6-dicyano-quinone (DDQ) is reported. The corresponding oxime ethers are obtained in good yields.
引用
收藏
页码：1235 / 1238
页数：4
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