Oral Dispersible System: A New Approach in Drug Delivery System

被引:44
|
作者
Hannan, P. A. [1 ]
Khan, J. A. [1 ]
Khan, A. [1 ]
Safiullah, S. [1 ]
机构
[1] Univ Peshawar, Dept Pharm, Khyber Pakhtunkhwa 25000, Pakistan
关键词
Fast dissolving/disintegrating tablets; orodispersible tablets; GIT; bioavailability; first pass metabolism; superdisintegrants; RAPIDLY DISINTEGRATING TABLETS; MOUTH DISSOLVING TABLETS; FORMULATION;
D O I
10.4103/0250-474X.180244
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Dosage form is a mean used for the delivery of drug to a living body. In order to get the desired effect the drug should be delivered to its site of action at such rate and concentration to achieve the maximum therapeutic effect and minimum adverse effect. Since oral route is still widely accepted route but having a common drawback of difficulty in swallowing of tablets and capsules. Therefore a lot of research has been done on novel drug delivery systems. This review is about oral dispersible tablets a novel approach in drug delivery systems that are now a day's more focused in formulation world, and laid a new path that, helped the patients to build their compliance level with the therapy, also reduced the cost and ease the administration especially in case of pediatrics and geriatrics. Quick absorption, rapid onset of action and reduction in drug loss properties are the basic advantages of this dosage form.
引用
收藏
页码:2 / 7
页数:6
相关论文
共 50 条
  • [41] NEW DRUG DELIVERY SYSTEM HELPS MENOPAUSE
    不详
    NEW SCIENTIST, 1986, 109 (1501) : 21 - 21
  • [42] New nanoscale pulsatile drug delivery system
    Liu, XM
    Yang, B
    Wang, YL
    Wang, JY
    CHEMISTRY OF MATERIALS, 2005, 17 (11) : 2792 - 2795
  • [43] A new concept of drug delivery system in oncology
    Matsumura, Yasuhiro
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2010, 26 : S63 - S63
  • [44] An approach to formulating an oral floating drug delivery system for dexchlorpheniramine maleate using factorial design
    Alabazi, M. Y.
    Elzein, H.
    PHARMAZIE, 2012, 67 (07): : 611 - 617
  • [45] SELF EMULSIFYING DRUG DELIVERY SYSTEM (SEDDS): A CONVENTIONAL AND ALTERNATIVE APPROACH TO IMPROVE ORAL BIOAVILABILITY
    Rajeshwar, V.
    Shrivastava, Birendra
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2018, 9 (08): : 3114 - 3127
  • [46] Design and development of a self-nanoemulsifying drug delivery system for telmisartan for oral drug delivery
    Patel, Jaydeep
    Kevin, Garala
    Patel, Anjali
    Raval, Mihir
    Sheth, Navin
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION, 2011, 1 (02) : 112 - 118
  • [47] In vivo evaluation of self emulsifying drug delivery system for oral delivery of nevirapine
    Chudasama, A. S.
    Patel, V. V.
    Nivsarkar, M.
    Vasu, Kamala K.
    Shishoo, C. J.
    INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2014, 76 (03) : 218 - 224
  • [48] IMPROVED ORAL DELIVERY OF ROSUVASTATIN BY USING SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM
    Subramanian, N.
    Sekar, P. Chandra
    Abimanyu, S.
    Sharavanan, S. P.
    Gayathri, R.
    Meenakshi, A.
    Nithyakalyani, M.
    ADVANCES IN NANOSCIENCE AND NANOTECHNOLOGY, 2013, 678 : 286 - 290
  • [49] A supersaturating drug delivery system to enhance the oral bioavailability of nilotinib
    Zhu, Shuzhen
    Yu, Ruilian
    Qian, Guangsheng
    Deng, Li
    JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2022, 68
  • [50] Biocompatible and Biomaterials Application in Drug Delivery System in Oral Cavity
    Hakim, Lotfollah Kamali
    Yazdanian, Mohsen
    Alam, Mostafa
    Abbasi, Kamyar
    Tebyaniyan, Hamid
    Tahmasebi, Elahe
    Khayatan, Danial
    Seifalian, Alexander
    Ranjbar, Reza
    Yazdanian, Alireza
    EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2021, 2021