Canakinumab treatment in four children with colchicine resistant familial mediterranean fever

被引：0

作者：

Ozkan, Solmaz ^{[1
]}

Atas, Bulent

机构：

[1] Cumra State Hosp, Cumra, Konya, Turkey

来源：

JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION | 2017年 / 67卷 / 06期

关键词：

Familial Mediterranean fever; Anakinra; Canakinumab; EFFICACY;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Familial Mediterranean Fever (FMF) is an autosomal recessive and autoinflammatory disease, characterized with inflammation of serous membranes such as peritoneum, pleura, synovium with fever and pain. Colchicine is the main treatment of FMF, but 5-10 % of patients are unresponsive to colchicine. We report using anti-interleukin-1 agents anakinra and canakinumab in four colchicine-resistant patients who were successfully treated. Three of the patients were siblings.

引用

页码：945 / 947

页数：3

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