Challenges with chromone as a privileged scaffold in drug discovery

被引：35
|
作者：
Silva, Carlos F. M.
Batista, Vasco F.
Pinto, Diana C. G. A. [1 ,2 ]
Silva, Artur M. S.
机构：
[1] Univ Aveiro, Dept Chem, Campus Univ Santiago, P-3810193 Aveiro, Portugal
[2] Univ Aveiro, QOPNA, Campus Univ Santiago, P-3810193 Aveiro, Portugal
来源：
EXPERT OPINION ON DRUG DISCOVERY | 2018年 / 13卷 / 09期
关键词：
Chromones; drug discovery; active principals; biological activities;
D O I：
10.1080/17460441.2018.1494720
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：795 / 798
页数：4
相关论文
共 50 条
  • [41] Discovery of novel A3 adenosine receptor ligands based on chromone scaffold
    Gaspar, Alexandra
    Reis, Joana
    Kachler, Sonja
    Paoletta, Silvia
    Uriarte, Eugenio
    Klotz, Karl-Norbert
    Moro, Stefano
    Borges, Fernanda
    BIOCHEMICAL PHARMACOLOGY, 2012, 84 (01) : 21 - 29
  • [42] Discovery of the first A1 adenosine receptor ligand based on the chromone scaffold
    Cagide, F.
    Reis, J.
    Gaspar, A.
    Chavarria, D.
    Kachler, S.
    Klotz, K. N.
    Gomes, L. R.
    Low, J. N.
    Vilar, S.
    Hripcsak, G.
    Borges, F.
    RSC ADVANCES, 2016, 6 (52) : 46972 - 46976
  • [43] Natural product derived privileged scaffolds in drug discovery
    Brimble, Margaret
    Davison, Emma
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 258
  • [44] Recent advances of quinones as a privileged structure in drug discovery
    Zhang, Li
    Zhang, Guiying
    Xu, Shujing
    Song, Yuning
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 223
  • [45] Natural product derived privileged scaffolds in drug discovery
    Davison, Emma K.
    Brimble, Margaret A.
    CURRENT OPINION IN CHEMICAL BIOLOGY, 2019, 52 : 1 - 8
  • [46] Scaffold hopping approaches for dual-target antitumor drug discovery: opportunities and challenges
    Mishra, Anshul
    Thakur, Amandeep
    Sharma, Ram
    Onuku, Raphael
    Kaur, Charanjit
    Liou, Jing Ping
    Hsu, Sung-Po
    Nepali, Kunal
    EXPERT OPINION ON DRUG DISCOVERY, 2024, 19 (11) : 1355 - 1381
  • [47] Pyrrolotriazinone as an Underexplored Scaffold in Drug Discovery
    Ge, Tony
    Cintrat, Jean-Christophe
    PHARMACEUTICALS, 2021, 14 (12)
  • [48] Bispidine as a Privileged Scaffold
    Tomassoli, Isabelle
    Guendisch, Daniela
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2016, 16 (11) : 1314 - 1342
  • [49] 2-Aminothiazole: A privileged scaffold for the discovery of anti-cancer agents
    Wan, Yichao
    Long, Jiabing
    Gao, Han
    Tang, Zilong
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 210
  • [50] Solid-Phase Synthesis of Tetramic Acid via Resin-Bound Enol Ethers as a Privileged Scaffold in Drug Discovery
    Schutznerova, Eva
    Oliver, Allen G.
    Pribylka, Adam
    Krchnak, Viktor
    ADVANCED SYNTHESIS & CATALYSIS, 2018, 360 (19) : 3693 - 3699
12345