Palladium-catalyzed C-H olefination of uracils and caffeines using molecular oxygen as the sole oxidant

被引：14
|
作者：
Zhang, Xinyu [1 ,2 ]
Su, Lv [1 ,2 ]
Qiu, Lin [1 ,2 ]
Fan, Zhenwei [1 ,2 ]
Zhang, Xiaofeng [1 ,2 ]
Lin, Shen [1 ,2 ]
Huang, Qiufeng [1 ,2 ]
机构：
[1] Fujian Normal Univ, Coll Chem & Chem Engn, Fuzhou 350007, Peoples R China
[2] Fujian Key Lab Polymer Mat, Fuzhou 350007, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2017年 / 15卷 / 16期
基金：
中国国家自然科学基金;
关键词：
DEHYDROGENATIVE HECK REACTIONS; FLUORESCENT CORE FRAMEWORKS; AMINO-ACID LIGANDS; BOND ACTIVATION; MECHANISTIC FEATURES; ATMOSPHERIC DIOXYGEN; OPTICAL-PROPERTIES; DIRECTING GROUPS; ALKENYLATION; FUNCTIONALIZATION;
D O I：
10.1039/c7ob00616k
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The palladium-catalyzed oxidative C-H olefination of uracils or caffeines with alkenes using an atmospheric pressure of molecular oxygen as the sole oxidant has been disclosed. This novel strategy offers an efficient and environmentally friendly method to biologically important C5-alkene uracil derivatives or C8-alkene caffeine derivatives.
引用
收藏
页码：3499 / 3506
页数：8
相关论文
共 50 条
  • [1] Palladium-Catalyzed C-H Direct Arylation of Uracils and Caffeines with Arenes Using Molecular Oxygen as the Sole Oxidant
    Pan, Guoshuai
    Wu, Kongchuan
    Deng, Zeying
    Zhang, Xinyu
    Zhang, Xiaofeng
    Lin, Shen
    Huang, Qiufeng
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2018, 38 (08) : 2076 - 2084
  • [2] Palladium-Catalyzed Olefination and Arylation of Polyfluoroarenes Using Molecular Oxygen as the Sole Oxidant
    Huang, Qiufeng
    Zhang, Xinyu
    Qiu, Lin
    Wu, Jiajun
    Xiao, Hanbing
    Zhang, Xiaofeng
    Lin, Shen
    ADVANCED SYNTHESIS & CATALYSIS, 2015, 357 (16-17) : 3753 - 3757
  • [3] Direct Access to Isoindolinone Derivatives by Palladium-Catalyzed C-H Activation and Isocyanide Insertion by Using Molecular Oxygen as the Sole Oxidant
    Wang, Dongqi
    Cai, Sheng
    Ben, Rong
    Zhou, Yang
    Li, Xingwei
    Zhao, Jing
    Wei, Wei
    Qian, Yong
    SYNTHESIS-STUTTGART, 2014, 46 (15): : 2045 - 2050
  • [4] Palladium-Catalyzed C-H Homocoupling of Furans and Thiophenes Using Oxygen as the Oxidant
    Li, Na-Na
    Zhang, Yan-Lei
    Mao, Shuai
    Gao, Ya-Ru
    Guo, Dong-Dong
    Wang, Yong-Qiang
    ORGANIC LETTERS, 2014, 16 (10) : 2732 - 2735
  • [5] Palladium Catalyzed C-H Olefination of Indolizines at the 1-Position with Molecular Oxygen as the Terminal Oxidant
    Lu, Mingzhu
    Shi, Fei
    Ji, Meishan
    Kan, Yuhe
    Hu, Huayou
    ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2019, 8 (08) : 1555 - 1560
  • [6] Palladium-catalyzed diacetoxylation of alkenes with molecular oxygen as sole oxidant
    Wang, Azhong
    Jiang, Huanfeng
    Chen, Huoji
    Journal of the American Chemical Society, 2009, 131 (11): : 3846 - 3847
  • [7] Palladium-Catalyzed Diacetoxylation of Alkenes with Molecular Oxygen as Sole Oxidant
    Wang, Azhong
    Jiang, Huanfeng
    Chen, Huoji
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (11) : 3846 - +
  • [8] Palladium-catalyzed C-7 alkenylation of indolines using molecular oxygen as the sole oxidant
    Yang, Dong
    Mao, Shuai
    Gao, Ya-Ru
    Guo, Dong-Dong
    Guo, Shi-Huan
    Li, Bin
    Wang, Yong-Qiang
    RSC ADVANCES, 2015, 5 (30): : 23727 - 23736
  • [9] Palladium-Catalyzed C-H Alkoxycarbonylation of Caffeines: Synthesis of 8-Ester-substituted Caffeines
    Su, Lu
    Xiao, Hanbing
    Yuan, Yumeng
    Zhang, Xiaofeng
    Lin, Shen
    Huang, Qiufeng
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 37 (03) : 630 - 635
  • [10] Palladium-Catalyzed C-H Olefination for Nucleic Acid Production
    Xie, Ruoqian
    Han, Yunxi
    Luo, Wenhao
    Zhao, Qin
    Li, Yangyan
    Chen, Gang
    CURRENT PROTOCOLS, 2023, 3 (07):
12345