Two new terpenes from Tripterygium wilfordii

被引：7
|
作者：
Le Li, Bo [1 ]
Shen, Qian [1 ]
Jin, Mei Na [1 ]
Duan, Hong Quan [1 ]
机构：
[1] Tianjin Med Univ, Sch Pharmaceut Sci, Res Ctr Basic Med Sci, Tianjin 300070, Peoples R China
来源：
CHINESE CHEMICAL LETTERS | 2010年 / 21卷 / 07期
关键词：
Tripterygium wilfordii; Sesquiterpene alkaloid; Diterpene; Immunosuppressive activity; SESQUITERPENE ALKALOIDS; TRIPDIOLIDE; HYPOGLAUCUM; TRIPTOLIDE; DITERPENES;
D O I：
10.1016/j.cclet.2010.03.007
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Two new terpenes, wilfornine H (1) and triptobenzene Q (2) were isolated from Tripterygium wilfordii, as well as 11 terpenes. Their structures were elucidated by spectroscopic methods. Compounds 5, 9-13 showed significant immunosuppressive activities. (C) 2010 Hong Quan Duan. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码：827 / 829
页数：3
相关论文
共 50 条
  • [41] Immunosuppressive sesquiterpene alkaloids from Tripterygium wilfordii
    Duan, HQ
    Takaishi, Y
    Momota, H
    Ohmoto, Y
    Taki, T
    Jia, YF
    Li, D
    JOURNAL OF NATURAL PRODUCTS, 2001, 64 (05): : 582 - 587
  • [42] ABIETANE DITERPENES FROM TRIPTERYGIUM-WILFORDII
    WU, XY
    QIN, GW
    XU, RS
    FAN, DJ
    PLANTA MEDICA, 1994, 60 (02) : 189 - 189
  • [43] Sesquiterpene alkaloids from Tripterygium hypoglaucum and Tripterygium wilfordii:: A new class of potent anti-HIV agents
    Duan, HQ
    Takaishi, Y
    Imakura, Y
    Jia, YF
    Li, D
    Cosentino, LM
    Lee, KH
    JOURNAL OF NATURAL PRODUCTS, 2000, 63 (03): : 357 - 361
  • [44] New 18(4→3)-Abeo-Abietanoids from Tripterygium wilfordii
    Ni, Lin
    Zang, Ying-da
    Yang, Jing-zhi
    Li, Chuang-jun
    Ma, Jie
    Zhang, Dong-ming
    MOLECULES, 2018, 23 (10):
  • [45] New abietane-type diterpene glycosides from the roots of Tripterygium wilfordii
    Li, Hong-Mei
    Wan, Da-Wu
    Li, Rong-Tao
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2015, 17 (07) : 761 - 766
  • [46] Wilfordonols A-D: four new norsesquiterpenes from the leaves of Tripterygium wilfordii
    Ni, Lin
    Zhou, Xing
    Ma, Jie
    Zhang, Xiao-Mei
    Li, Chuang-Jun
    Li, Li
    Yang, Da-Jian
    Shao, Yang-Yang
    Zhou, Si-Bai
    Zhang, Tian-Tai
    Zhang, Dong-Ming
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2015, 17 (06) : 615 - 624
  • [47] Three new sesquiterpenoid alkaloids from the roots of Tripterygium wilfordii and its cytotoxicity
    Ye, Hong Liang
    Liu, Yan
    Pan, Juan
    Guan, Wei
    Liu, Yuan
    Li, Xiao Mao
    Wang, Si Yi
    Algradi, Adnan Mohammed
    Yang, Bing You
    Kuang, Hai Xue
    NATURAL PRODUCT RESEARCH, 2022, 36 (15) : 3979 - 3987
  • [48] POLYHYDROXYAGAROFURAN DERIVATIVES FROM TRIPTERYGIUM-WILFORDII-H
    TAKAISHI, Y
    UJITA, K
    KIDA, K
    SHIBUYA, M
    TOMIMATSU, T
    PHYTOCHEMISTRY, 1987, 26 (09) : 2581 - 2584
  • [49] A diterpenoid and triterpenes from tissue cultures of Tripterygium wilfordii
    Nakano, K
    Oose, Y
    Masuda, Y
    Kamada, H
    Takaishi, Y
    PHYTOCHEMISTRY, 1997, 45 (02) : 293 - 296
  • [50] Chemical constituents of Tripterygium wilfordii
    Yang, GZ
    Yin, XQ
    Li, YC
    HELVETICA CHIMICA ACTA, 2000, 83 (12) : 3344 - 3350
12345