Hedgehog signaling induces PDL-1 expression and subsequently inactivates effector T cell function and promotes gastric cancer cell proliferation

被引：0
|
作者：
Chakrabarti, Jayati
Syu, LiJyun
Holokai, Loryn
Steel, Nina
Chang, Julie
Dlugosz, Andrzej
Zavros, Yana
机构：
来源：
FASEB JOURNAL | 2018年 / 32卷 / 01期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
610.1
引用
收藏
页数：3
相关论文
共 50 条
  • [41] Aberrant activation of hedgehog signaling promotes cell proliferation via the transcriptional activation of forkhead Box M1 in colorectal cancer cells
    DeJie Wang
    Guohui Hu
    Ying Du
    Cheng Zhang
    Quqin Lu
    Nonghua Lv
    Shiwen Luo
    Journal of Experimental & Clinical Cancer Research, 36
  • [42] Aberrant activation of hedgehog signaling promotes cell proliferation via the transcriptional activation of forkhead Box M1 in colorectal cancer cells
    Wang, Dejie
    Hu, Guohui
    Du, Ying
    Zhang, Cheng
    Lu, Quqin
    Lv, Nonghua
    Luo, Shiwen
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2017, 36 : 1 - 11
  • [43] Concomitant targeting of Hedgehog signaling and MCL-1 synergistically induces cell death in Hedgehog-driven cancer cells
    Meister, Michael Torsten
    Boedicker, Cathinka
    Linder, Benedikt
    Koegel, Donat
    Klingebiel, Thomas
    Fulda, Simone
    CANCER LETTERS, 2019, 465 : 1 - 11
  • [44] Hedgehog signaling promotes cell growth and proliferation by regulating expression of Rb/E2F pathway components.
    Duman-Scheel, M
    Weng, L
    Xin, S
    Du, W
    DEVELOPMENTAL BIOLOGY, 2001, 235 (01) : 233 - 233
  • [45] IRF4 impedes human CD8 T cell function and promotes cell proliferation and PD-1 expression
    Hirsch, Thibault
    Neyens, Damien
    Duhamel, Celine
    Bayard, Alexandre
    Vanhaver, Christophe
    Luyckx, Mathieu
    de Oyanguren, Francisco Sala
    Wildmann, Claude
    Dauguet, Nicolas
    Squifflet, Jean-Luc
    Montiel, Virginie
    Deschamps, Melanie
    van der Bruggen, Pierre
    CELL REPORTS, 2024, 43 (07):
  • [46] RADIOMICS FOR THE NON-INVASIVE ASSESSMENT OF THE PDL-1 EXPRESSION IN PATIENTS WITH NON-SMALL CELL LUNG CANCER BRAIN METASTASES
    Meissner, A.
    Gutsche, R.
    Galldiks, N.
    Kocher, M.
    Junger, S.
    Eich, M.
    Nogova, L.
    Schmidt, N.
    Ruge, M.
    Goldbrunner, R.
    Proescholdt, M.
    Grau, S.
    Lohmann, P.
    NEURO-ONCOLOGY, 2022, 24
  • [47] BST2 promotes cell proliferation, migration and induces NF-κB activation in gastric cancer
    Liu, Weiyu
    Cao, Yong
    Guan, Yadi
    Zheng, Changqing
    BIOTECHNOLOGY LETTERS, 2018, 40 (07) : 1015 - 1027
  • [48] BST2 promotes cell proliferation, migration and induces NF-κB activation in gastric cancer
    Weiyu Liu
    Yong Cao
    Yadi Guan
    Changqing Zheng
    Biotechnology Letters, 2018, 40 : 1015 - 1027
  • [49] Autocrine Sonic hedgehog signaling promotes gastric cancer proliferation through induction of phospholipase Cγ1 and the ERK1/2 pathway
    Zhai Ertao
    Chen Jianhui
    Chen Chuangqi
    Qin Changjiang
    Chen Sile
    He Yulong
    Wu Hui
    Cai Shirong
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2016, 35
  • [50] Autocrine Sonic hedgehog signaling promotes gastric cancer proliferation through induction of phospholipase Cγ1 and the ERK1/2 pathway
    Zhai Ertao
    Chen Jianhui
    Chen Chuangqi
    Qin Changjiang
    Chen Sile
    He Yulong
    Wu Hui
    Cai Shirong
    Journal of Experimental & Clinical Cancer Research, 35
12345