Asymmetric reduction of substituted fluorenones with aluminium lithium hydride in the presence of chiral amino alcohols

被引：3
|
作者：
Yu, ZR [1 ]
López-Calahorra, F [1 ]
Velasco, D [1 ]
机构：
[1] Univ Barcelona, Fac Quim, Dept Quim Organ, E-08028 Barcelona, Spain
来源：
TETRAHEDRON-ASYMMETRY | 2000年 / 11卷 / 15期
关键词：
D O I：
10.1016/S0957-4166(00)00277-9
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The enantioselective reduction of substituted fluorenones by aluminium lithium hydride in the presence of different chiral amino alcohols has been investigated. The best conditions found were also assayed with a multi-substituted fluorenone achieving the corresponding fluorenol compound with high enantiomeric excess. Shorter reaction times with high conversion yields were found when compared with borane reductions. (C) 2000 Elsevier Science Ltd. All rights reserved.
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页码：3227 / 3230
页数：4
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