Antisense oligonucleotides as inhibitors of genes that regulate AP-1: Pharmacology and clinical development

被引：7
|
作者：
Dean, NM [1 ]
McKay, RA [1 ]
Holmlund, J [1 ]
机构：
[1] ISIS Pharmaceut, Carlsbad, CA 92008 USA
来源：
ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT | 1998年 / 8卷 / 02期
关键词：
D O I：
10.1089/oli.1.1998.8.147
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：147 / 151
页数：5
相关论文
共 50 条
  • [31] Antisense oligonucleotides as inhibitors of signal transduction: Development from research tools to therapeutic agents
    Dean, NM
    McKay, R
    Miraglia, L
    Geiger, T
    Muller, M
    Fabbro, D
    Bennett, CF
    BIOCHEMICAL SOCIETY TRANSACTIONS, 1996, 24 (03) : 623 - 629
  • [32] Hijacking of the AP-1 Signaling Pathway during Development of ATL
    Gazon, Helene
    Barbeau, Benoit
    Mesnard, Jean-Michel
    Peloponese, Jean-Marie, Jr.
    FRONTIERS IN MICROBIOLOGY, 2018, 8
  • [33] Identification and preclinical pharmacology of antisense oligonucleotides targeted to human SOD1 for the treatment of ALS
    Swayze, Eric
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [34] AP-1, CREB and CBP transcription factors differentially regulate the tyrosine hydroxylase gene
    Ghee, M
    Baker, H
    Miller, JC
    Ziff, EB
    MOLECULAR BRAIN RESEARCH, 1998, 55 (01): : 101 - 114
  • [35] MODULATION OF PREIMPLANTATION EMBRYONIC-DEVELOPMENT BY ANTISENSE OLIGONUCLEOTIDES TO MAJOR HISTOCOMPATIBILITY COMPLEX GENES
    XU, YX
    JIN, P
    WARNER, CM
    BIOLOGY OF REPRODUCTION, 1993, 48 (05) : 1042 - 1046
  • [36] Bone development and disease regulated by AP-1 (Fos/Jun)
    Wagner, E.
    Bozec, A.
    Bakiri, L.
    FEBS JOURNAL, 2009, 276 : 27 - 28
  • [37] Functions of FOS/AP-1 proteins in bone development and beyond
    Wagner, E. F.
    Bakiri, L.
    Bozec, A.
    BONE, 2012, 51 (06) : S14 - S14
  • [38] Development of an oral formulation for ICAM-1 antisense oligonucleotides.
    Stepkowski, SM
    Chen, W
    Geary, R
    Wang, ME
    Condon, T
    Stecker, K
    Bennett, CF
    TRANSPLANTATION, 2000, 69 (08) : S412 - S412
  • [39] The clathrin adaptor AP-1 complex and Arf1 regulate planar cell polarity in vivo
    Jose Maria Carvajal-Gonzalez
    Sophie Balmer
    Meg Mendoza
    Aurore Dussert
    Giovanna Collu
    Angel-Carlos Roman
    Ursula Weber
    Brian Ciruna
    Marek Mlodzik
    Nature Communications, 6
  • [40] Determination of binding constant of transcription factor AP-1 and DNA - Application of inhibitors
    Kwon, H
    Park, S
    Lee, S
    Lee, DK
    Yang, CH
    EUROPEAN JOURNAL OF BIOCHEMISTRY, 2001, 268 (03): : 565 - 572
12345