(S)-(3-hydroxy-4,4-dimethyl-2-oxopyrrolidin-1-yl) acetic acid as a solid supported chiral auxiliary in the asymmetric synthesis of β2-homoarylglycines

被引：13
|
作者：
Akkari, R
Calmès, M
Di Malta, D
Escale, FO
Martinez, J
机构：
[1] Univ Montpellier I, Lab Aminoacides Peptides & Prot, CNRS, UMR 5810, F-34095 Montpellier 5, France
[2] Univ Montpellier 2, Lab Aminoacides Peptides & Prot, CNRS, UMR 5810, F-34095 Montpellier 5, France
来源：
TETRAHEDRON-ASYMMETRY | 2003年 / 14卷 / 09期
关键词：
D O I：
10.1016/S0957-4166(03)00178-2
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Diastereoselective additions of the resin-supported (S)-(3-hydroxy-4,4-dimethyl-2-oxopyrrolidin-1-yl) acetic acid to phthalimidomethyl aryl ketenes allow solid phase preparation of beta(2)-homoarylglycines with reasonable degrees of stereoselectivity. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：1223 / 1228
页数：6
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