Tomographic features of branching vascular networks in polypoidal choroidal vasculopathy

被引:148
|
作者
Sato, Taku [1 ]
Kishi, Shoji [1 ]
Watanabe, Goro [1 ]
Matsumoto, Hidetaka [1 ]
Mukai, Ryo [1 ]
机构
[1] Gunma Univ, Sch Med, Dept Ophthalmol, Maebashi, Gunma 3718511, Japan
关键词
Age-related macular degeneration; Choroidal neovascularization; Fluorescein angiography; Optical coherence tomography; Polypoidal choroidal vasculopathy;
D O I
10.1097/01.iae.0000249386.63482.05
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To identify the tomographic features of the branching vascular networks in patients with polypoidal choroidal vasculopathy (PCV). Methods: We prospectively performed third -generation optical coherence tomography (OCT) and fluorescein angiography for 44 eyes of 42 patients (mean age SID, 67.1 +/- 9.1 years) with PCV. All eyes had branching vascular networks and polypoidal lesions that were confirmed by indocyanine green angiography. Results: OCT showed double reflective layers that consisted of retinal pigment epithelium (RPE) and another highly reflective layer beneath the RPE ("double-layer sign") in the area of the branching network vessels in 26 (59%) of 44 eyes. The remaining 18 eyes had no double-layer sign, but 17 (94%) of 18 eyes had a slightly elevated RPE. A serous retinal detachment was present in 23 (88%) of 26 eyes with a double-layer sign, while only 1 (6%) of 18 eyes without the sign had a serous retinal detachment. Conclusions: In PCV, the double-layer sign is seen frequently in the area of the network vessels, particularly in eyes with a serous retinal detachment. The sign may reflect fluid accumulation between RPE and Bruch membrane resulting from leakage from the network of abnormal vessels.
引用
收藏
页码:589 / 594
页数:6
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