Association of social distancing and face mask use with risk of COVID-19

被引：119

作者：

Kwon, Sohee ^{[1
,2
,3
]}

Joshi, Amit D. ^{[1
,2
,3
]}

Lo, Chun-Han ^{[1
,2
,3
]}

Drew, David A. ^{[1
,2
,3
]}

Nguyen, Long H. ^{[1
,2
,3
,4
]}

Guo, Chuan-Guo ^{[1
,2
,3
,5
]}

Ma, Wenjie ^{[1
,2
,3
]}

Mehta, Raaj S. ^{[1
,2
,3
]}

Shebl, Fatma Mohamed ^{[2
,6
]}

Warner, Erica T. ^{[1
,2
,7
]}

Astley, Christina M. ^{[2
,8
,9
]}

Merino, Jordi ^{[10
,11
,12
]}

Murray, Benjamin ^{[13
]}

Wolf, Jonathan ^{[14
]}

Ourselin, Sebastien ^{[13
]}

Steves, Claire J. ^{[15
]}

Spector, Tim D. ^{[15
]}

Hart, Jaime E. ^{[2
,16
,17
]}

Song, Mingyang ^{[1
,2
,3
,18
,19
]}

VoPham, Trang ^{[20
,21
]}

Chan, Andrew T. ^{[1
,2
,3
,10
,22
]}

机构：

[1] Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA 02114 USA

[2] Harvard Med Sch, Boston, MA 02115 USA

[3] Massachusetts Gen Hosp, Div Gastroenterol, Boston, MA 02114 USA

[4] Harvard TH Chan Sch Publ Hlth, Dept Biostat, Boston, MA USA

[5] Univ Hong Kong, Li Ka Shing Fac Med, Dept Med, Hong Kong, Peoples R China

[6] Massachusetts Gen Hosp, Med Practice Evaluat Ctr, Boston, MA 02114 USA

[7] Massachusetts Gen Hosp, Harvard MGH Ctr Gen Vulnerable Populat & Hlth Dis, Boston, MA 02114 USA

[8] Boston Childrens Hosp, Div Endocrinol & Computat Epidemiol, Boston, MA USA

[9] Broad Inst MIT & Harvard, Cambridge, MA 02142 USA

[10] Massachusetts Gen Hosp, Ctr Genom Med, Diabet Unit, Boston, MA 02114 USA

[11] Broad Inst & Harvard, Programs Metab & Med & Populat Genet, Cambridge, MA 02142 USA

[12] Harvard Med Sch, Dept Med, Boston, MA 02115 USA

[13] Kings Coll London, Sch Biomed Engn & Imaging Sci, London, England

[14] Zoe Ltd, London, England

[15] Kings Coll London, Dept Twin Res & Genet Epidemiol, London, England

[16] Brigham & Hosp, Dept Med, Channing Div Network Med, Boston, MA 02115 USA

[17] Harvard TH Chan Sch Publ Hlth, Dept Environm Hlth, Exposure Epidemiol & Risk Program, Boston, MA USA

[18] Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA

[19] Harvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA USA

[20] Fred Hutchinson Canc Res Ctr, Program Epidemiol, Div Publ Hlth Sci, Seattle, WA USA

[21] Univ Washington, Sch Publ Hlth, Dept Epidemiol, Seattle, WA 98195 USA

[22] Harvard TH Chan Sch Publ Hlth, Dept Immunol & Infect Dis, Boston, MA 02115 USA

来源：

NATURE COMMUNICATIONS | 2021年 / 12卷 / 01期

基金：

美国国家卫生研究院; 英国惠康基金; 英国科研创新办公室; 欧盟地平线“2020”; 英国工程与自然科学研究理事会;

关键词：

TRENDS;

D O I：

10.1038/s41467-021-24115-7

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Given the continued burden of COVID-19 worldwide, there is a high unmet need for data on the effect of social distancing and face mask use to mitigate the risk of COVID-19. We examined the association of community-level social distancing measures and individual face mask use with risk of predicted COVID-19 in a large prospective U.S. cohort study of 198,077 participants. Individuals living in communities with the greatest social distancing had a 31% lower risk of predicted COVID-19 compared with those living in communities with poor social distancing. Self-reported 'always' use of face mask was associated with a 62% reduced risk of predicted COVID-19 even among individuals living in a community with poor social distancing. These findings provide support for the efficacy of mask-wearing even in settings of poor social distancing in reducing COVID-19 transmission. Despite mass vaccination campaigns in many parts of the world, continued efforts at social distancing and face mask use remain critically important in reducing the spread of COVID-19. Estimating the effectiveness of COVID-19 control measures requires large prospective data including symptoms and personal risk factors. Here, the authors used data from smartphone-based application and found that individual face mask use was associated with a 64% reduced risk of COVID-19 symptoms.

引用

页数：10

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