One-pot synthesis of 1,4-disubstituted 1,2,3-triazoles from terminal acetylenes and in situ generated azides

被引：72

作者：

Odlo, Kristin ^{[1
]}

Hoydahl, Edmund Andre ^{[1
]}

Hansen, Trond Vidar ^{[1
]}

机构：

[1] Univ Oslo, Sch Pharm, Dept Pharmaceut Chem, N-0316 Oslo, Norway

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 12期

关键词：

one-pot reactions; 1,2,3-triazoles; cycloadditions;

D O I：

10.1016/j.tetlet.2007.01.130

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,4-Disubstituted 1,2,3-triazoles were obtained by a high-yielding copper(1) catalyzed 1,3-dipolar cycloaddition reaction between in situ generated azides and terminal acetylenes. This one-pot, two-step procedure tolerates most functional groups and circumvents the problems associated with the isolation of potentially toxic and explosive organic azides. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：2097 / 2099

页数：3

共 50 条

[21] Copper(I)-Catalyzed Synthesis of 1,4-Disubstituted 1,2,3-Triazoles from Azidoformates and Aryl Terminal Alkynes
Lee, Heejin
Lee, Jae Kyun
Min, Sun-Joon
Seo, Hyeonglim
Lee, Youngbok
Rhee, Hakjune
JOURNAL OF ORGANIC CHEMISTRY, 2018, 83 (08): : 4805 - 4811
[22] Ultrasonic-assisted synthesis of 1,4-disubstituted 1,2,3-triazoles via various terminal acetylenes and azide and their quorum sensing inhibition
Zhang, Da-wei
Zhang, Yu-min
Li, Jing
Zhao, Tian-qi
Gu, Qiang
Lin, Feng
ULTRASONICS SONOCHEMISTRY, 2017, 36 : 343 - 353
[23] Synthetic Routes for 1,4-disubstituted 1,2,3-triazoles: A Review
Kaushik, Chander P.
Sangwan, Jyoti
Luxmi, Raj
Kumar, Krishan
Pahwa, Ashima
CURRENT ORGANIC CHEMISTRY, 2019, 23 (08) : 860 - 900
[24] Sulfonamide tethered 1,4-disubstituted 1,2,3-triazoles: Synthesis and antibacterial evaluation
Yadav, Jyoti
Kaushik, C. P.
SYNTHETIC COMMUNICATIONS, 2024, 54 (07) : 536 - 552
[25] Synthesis, Characterization, and Antioxidant and Anticancer Activity of 1,4-Disubstituted 1,2,3-triazoles
Sahin, Irfan
Ozgeris, Fatma Betul
Kose, Muhammet
Bakan, Ebubekir
Tumer, Ferhan
JOURNAL OF MOLECULAR STRUCTURE, 2021, 1232
[26] One-pot chemoenzymatic synthesis of chiral disubstituted 1,2,3-triazoles in aqueous media
de Oliveira, Camila de Souza
de Andrade, Kleber Tellini
Omori, Alvaro Takeo
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2013, 91 : 93 - 97
[27] Cu(I)-catalyzed one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles via nucleophilic displacement and 1,3-dipolar cycloaddition
Sreedhar, B
Reddy, PS
Kumar, NS
TETRAHEDRON LETTERS, 2006, 47 (18) : 3055 - 3058
[28] One-pot synthesis of 1,2,3-triazoles from Michael reaction
Korea Research Institute of Chemical Technology, Daejeon 305-343, Korea, Republic of
不详
Bull. Korean Chem. Soc., 2008, 4 (723-724):
[29] One-pot synthesis of 1,2,3-triazoles from Michael reaction
Lee, Ihl Young Choi
Yu, Ok Jong
Lim, Hee-Jeong
Lee, Hyo Won
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2008, 29 (04): : 723 - 724
[30] One-pot multicomponent click synthesis of some novel 1,4-disubstituted-1H-1,2,3-triazoles from alkenes
Keshavarz, Mosadegh
IRANIAN CHEMICAL COMMUNICATION, 2018, 6 (02) : 134 - 142

← 1 2 3 4 5 →