Highly diastereoselective synthesis of two analogues of dihydrosphingosine

被引：33
|
作者：
Villard, R [1 ]
Fotiadu, F [1 ]
Buono, G [1 ]
机构：
[1] Ecole Natl Super Synth Proc & Ingn Chim Aix Marse, UMR 6516, F-13397 Marseille 20, France
来源：
TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 04期
关键词：
D O I：
10.1016/S0957-4166(98)00030-5
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Diastereomeric analogues 8 and 9 of dihydrosphingosine 2 with a shortened alkyl chain were obtained with high diastereoselectivity via addition of n-hexyl magnesium bromide or dihexylzinc to a chiral aldehyde 3, respectively. These compounds are precursors of new potentially hydrosoluble analogues of glycosphingolipides. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：607 / 611
页数：5
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