Does COPD risk vary by ethnicity? A retrospective cross-sectional study

被引:40
|
作者
Gilkes, Alexander [1 ]
Ashworth, Mark [1 ]
Schofield, Peter [1 ]
Harries, Timothy H. [1 ]
Durbaba, Stevo [1 ]
Weston, Charlotte [1 ]
White, Patrick [1 ]
机构
[1] Kings Coll London, Div Hlth & Social Care Res, Dept Primary Care & Publ Hlth Sci, 3rd Floor Addison House,Guys Campus, London SE1 1UL, England
来源
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE | 2016年 / 11卷
基金
美国国家卫生研究院;
关键词
COPD; smoking; ethnicity; RACIAL-DIFFERENCES; LUNG-FUNCTION; VENTILATORY FUNCTION; SMOKING; NICOTINE;
D O I
10.2147/COPD.S96391
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Background: Lower risk of COPD has been reported in black and Asian people, raising questions of poorer recognition or reduced susceptibility. We assessed prevalence and severity of COPD in ethnic groups, controlling for smoking. Method: A retrospective cross-sectional study using routinely collected primary care data in London. COPD prevalence, severity (% predicted forced expiratory volume in 1 second [FEV1]), smoking status, and treatment were compared between ethnic groups, adjusting for age, sex, smoking, deprivation, and practice clustering. Results: Among 358,614 patients in 47 general practices, 47.6% were white, 20% black, and 5% Asian. Prevalence of COPD was 1.01% overall, 1.55% in whites, 0.58% in blacks, and 0.78% in Asians. COPD was less likely in blacks (adjusted odds ratio [OR], 0.44; 95% confidence interval [CI] 0.39-0.51) and Asians (0.82; CI, 0.68-0.98) than whites. Black COPD patients were less likely to be current smokers (OR, 0.56; CI, 0.44-0.71) and more likely to be never-smokers (OR, 4.9; CI, 3.4-7.1). Treatment of patients with similar disease severity was similar irrespective of ethnic origin, except that long-acting muscarinic antagonists were prescribed less in black COPD patients (OR, 0.53; CI, 0.42-0.68). Black ethnicity was a predictor of poorer lung function (% predicted FEV1: B coefficient, -7.6; P<0.0001), an effect not seen when ethnic-specific predicted FEV1 values were used. Conclusion: Black people in London were half as likely as whites to have COPD after adjusting for lower smoking rates in blacks. It seems likely that the differences observed were due either to ethnic differences in the way cigarettes were smoked or to ethnic differences in susceptibility to COPD.
引用
收藏
页码:739 / 746
页数:8
相关论文
共 50 条
  • [21] COPD uncovered: a cross-sectional study to assess the socioeconomic burden of COPD in Japan
    Igarashi, Ataru
    Fukuchi, Yoshinosuke
    Hirata, Kazuto
    Ichinose, Masakazu
    Nagai, Atsushi
    Nishimura, Masaharu
    Yoshisue, Hajime
    Ohara, Kenichi
    Gruenberger, Jean-Bernard
    INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2018, 13 : 2629 - 2641
  • [22] Does the impact of bereavement vary between same and different gender partnerships? A representative national, cross-sectional study
    Timmins, Liadh
    Pitman, Alexandra
    King, Michael
    Gao, Wei
    Johnson, Katherine
    Yu, Peihan
    Braybrook, Debbie
    Roach, Anna
    Marshall, Steve
    Day, Elizabeth
    Rose, Ruth
    Clift, Paul
    Almack, Kathryn
    Yi, Deok Hee
    Bristowe, Katherine
    Harding, Richard
    PSYCHOLOGICAL MEDICINE, 2023, 53 (09) : 3849 - 3857
  • [23] Does parental concern about their child's future risk of overweight vary by their ethnic background? Cross-sectional analysis of a national cohort study
    Firman, Nicola
    Dezateux, Carol
    BMJ OPEN, 2019, 9 (08):
  • [24] FACTORS ASSOCIATED WITH MEDICATION ADHERENCE AMONG STABLE COPD PATIENTS: A CROSS-SECTIONAL RETROSPECTIVE STUDY IN CHINA
    Tao, T.
    Dong, X.
    Shao, R.
    VALUE IN HEALTH, 2019, 22 : S361 - S361
  • [25] Asthma and COPD in primary health care, quality according to national guidelines: a cross-sectional and a retrospective study
    Siw Carlfjord
    Malou Lindberg
    BMC Family Practice, 9
  • [26] Asthma and COPD in primary health care, quality according to national guidelines: a cross-sectional and a retrospective study
    Carlfjord, Siw
    Lindberg, Malou
    BMC FAMILY PRACTICE, 2008, 9 (1)
  • [27] Bone mineral status in COPD patients: A cross-sectional study
    Zmierczak, H.
    Derom, E.
    Behaegel, M.
    Demuynck, R.
    Myny, H.
    Vlieghe, H.
    Kaufman, J. M.
    Goemaere, S.
    OSTEOPOROSIS INTERNATIONAL, 2006, 17 : S54 - S54
  • [28] Associations between COPD related manifestations: a cross-sectional study
    Romme, Elisabeth A. P. M.
    McAllister, David A.
    Murchison, John T.
    Van Beek, Edwin J. R.
    Petrides, George S.
    Price, Cameron O. S.
    Rutten, Erica P. A.
    Smeenk, Frank W. J. M.
    Wouters, Emiel F. M.
    MacNee, William
    RESPIRATORY RESEARCH, 2013, 14
  • [29] Transitions between COPD groups: A cross-sectional study in Turkey
    Turan, P. A.
    Turan, O.
    Guldaval, F.
    Anar, C.
    Polat, G.
    Buyuksirin, M.
    RESPIRATORY MEDICINE, 2021, 178
  • [30] Do bronchiectasis worsens COPD - a cross-sectional pilot study
    Das, Soumya
    Barui, Hrishikesh
    Ghosh, Santanu
    Ghosh, Subhajit
    EUROPEAN RESPIRATORY JOURNAL, 2024, 64