ABC Transporters in Drug-Refractory Epilepsy: Limited Clinical Significance of Pharmacogenetics?

被引:27
|
作者
Cascorbi, I. [1 ]
机构
[1] Univ Hosp Schleswig Holstein, Inst Expt & Clin Pharmacol, Kiel, Germany
关键词
MULTIDRUG-RESISTANCE; P-GLYCOPROTEIN; POLYMORPHISM; EXPRESSION; GENE; ASSOCIATION;
D O I
10.1038/clpt.2009.237
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:15 / 18
页数:4
相关论文
共 50 条
  • [41] ABC transporters in drug-resistant epilepsy: mechanisms of upregulation and therapeutic approaches
    Leandro, Kevin
    Bicker, Joana
    Alves, Gilberto
    Falcao, Amilcar
    Fortuna, Ana
    PHARMACOLOGICAL RESEARCH, 2019, 144 : 357 - 376
  • [42] CLINICAL-EXPERIENCE WITH SOTALOL IN PATIENTS WITH DRUG-REFRACTORY VENTRICULAR ARRHYTHMIAS
    RUDER, MA
    ELLIS, T
    LEBSACK, C
    MEAD, RH
    SMITH, NA
    WINKLE, RA
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1989, 13 (01) : 145 - 152
  • [43] Neurological function and drug-refractory epilepsy in Sturge-Weber syndrome children: a retrospective analysis
    Yu Zhang
    Jiechao Niu
    Jiandong Wang
    Aojie Cai
    Yao Wang
    Guangshuai Wei
    Huaili Wang
    European Journal of Pediatrics, 2024, 183 : 1881 - 1890
  • [44] MR-guided stereotactic laser thermoablation of a hypothalamic hamartoma in a girl with drug-refractory epilepsy: clinical course and cost analysis
    Kohlhase, Konstantin
    Strzelczyk, Adam
    Porto, Luciana
    Beissel, Achim
    Curry, Daniel J.
    Rosenow, Felix
    Schubert-Bast, Susanne
    ZEITSCHRIFT FUR EPILEPTOLOGIE, 2021, 34 (03): : 324 - 330
  • [45] Neurological function and drug-refractory epilepsy in Sturge-Weber syndrome children: a retrospective analysis
    Zhang, Yu
    Niu, Jiechao
    Wang, Jiandong
    Cai, Aojie
    Wang, Yao
    Wei, Guangshuai
    Wang, Huaili
    EUROPEAN JOURNAL OF PEDIATRICS, 2024, 183 (04) : 1881 - 1890
  • [46] MR volumetric analysis of the piriform cortex and cortical amygdala in drug-refractory temporal lobe epilepsy
    Pereira, PMG
    Insausti, R
    Artacho-Pérula, E
    Salmenperä, T
    Kälviäinen, R
    Pitkänen, A
    AMERICAN JOURNAL OF NEURORADIOLOGY, 2005, 26 (02) : 319 - 332
  • [47] Research progress on the electrophysiological indicators to predict the efficacy of vagus nerve stimulation for drug-refractory epilepsy
    Li, Guangli
    Li, Zhenguang
    Liu, Yingting
    ACTA EPILEPTOLOGICA, 2024, 6 (01):
  • [48] Research progress on the electrophysiological indicators to predict the efficacy of vagus nerve stimulation for drug-refractory epilepsy
    Guangli Li
    Zhenguang Li
    Yingting Liu
    Acta Epileptologica, 2024, 6
  • [49] P53 and Ki-67 expression can predict drug-refractory epilepsy
    Aizpurua, M.
    Toledo, M.
    Martinez Ricarte, F.
    Ortega Aznar, A.
    Navarro, A.
    Palhua, R. L.
    Ramon y Cajal, S.
    Martinez Saez, E.
    VIRCHOWS ARCHIV, 2013, 463 (02) : 229 - 229
  • [50] AMIODARONE - CLINICAL EFFICACY AND TOXICITY IN 96 PATIENTS WITH RECURRENT, DRUG-REFRACTORY ARRHYTHMIAS
    FOGOROS, RN
    ANDERSON, KP
    WINKLE, RA
    SWERDLOW, CD
    MASON, JW
    CIRCULATION, 1983, 68 (01) : 88 - 94